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The similarities of the newborn pig to human infants in terms of body size, anatomy, and physiology provide a well-suited animal model to test questions that are not feasible or ethically possible in human infants. The pig also enables the use of clinical procedures and therapies (e.g., TPN, orogastric tube feeding, surgical intestinal resection) used in human infants that more closely simulate current medical practices. The advantages of newborn mice are lower cost and widely available genetic mouse models to test specific gene effects on GI and liver disease.
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