Department of Medicine

Clinical Research

Master
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Clinical research in the section includes both observational epidemiological studies, ranging from large cohorts to selected patient subgroups, and clinical trials of interventions targeting cardiovascular risk factors such as dyslipidemia and hypertension, including novel agents in development to improve cardiovascular disease prevention

See a list of our clinical research by investigator.

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Atherosclerosis Clinical Research Laboratory

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The Maria and Alando J. Ballantyne, M.D., Atherosclerosis Clinical Research Laboratory has more than three decades of experience in biobanking and currently stores >1.5 million samples in more than 70 ultralow-temperature (–80°C) freezers in dedicated climate-controlled freezer farm facilities, with an integrated barcoding system for sample tracking and a dedicated software program to maintain up-to-date sample inventory. The lab serves as the central lipid laboratory for the Atherosclerosis Risk in Communities (ARIC) study. Christie M. Ballantyne, M.D. is the director and Ron Hoogeveen, Ph.D. is the co-director.

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Clinical Trials

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Section faculty members conduct clinical trials to evaluate the effects of diet and drug interventions as well as the use of imaging modalities to detect and monitor atherosclerosis. Ongoing studies include NIH-supported projects and industry-sponsored research. Qualified participants are essential to medical research and make important contributions to improving medical practice and human health. Individuals interested in participating are encouraged to contact the study coordinator to determine eligibility.