Clinical and Translational Obesity Research Core

Content

The objective of the Clinical and Translational Research Core is to enhance and expand the translational research capabilities of investigators performing research studies in obesity and/or nutrition-related diseases. Obtaining human samples is often a challenging process and for many researchers, a significant research barrier.

Our Core will provide access to a biobank of obesity-relevant tissues. Additionally, we will facilitate collaborations among researchers by maintaining a database of obesity-related human research at both Baylor St. Luke’s Medical Center, Texas Children’s Hospital, and the USDA/ARS Children’s Nutrition Research Center. We will also provide consultative services to anyone embarking on a human nutrition- or obesity-related research project to both enhance the rigor of study, facilitate collaborations, and provide information on the nutrition-related resources available within the Texas Medical Center.

Tissue Biobank

The tissue biobank will contain adult and pediatric tissues across the age, sex, and BMI spectrum. Tissues that are currently available include:

Adolescents with severe obesity

Subcutaneous adipose tissue
Visceral adipose tissue
Liver
Plasma
Serum
Small intestine
Buffy coat
Red blood cells

NORC Human Research Study Repository

The CTORC hosts the NORC Human Research Study Repository, which is a data repository for human studies in nutrition and obesity. This repository maintains high level data on demographics, types of data available, and types of biospecimens collected through individual projects at participating H-NORC centers. Researchers who would like to collaborate can use this repository to identify completed and ongoing studies. All researchers who contribute data have the ability to independently search the repository. Researchers who have not contributed data can contact the core directors for assistance at CTORC@bcm.edu. The repository can be found at https://orit.research.bcm.edu/HNORCHumanResearch.