Use of Human Milk Cream to Decrease Length of Stay in Extremely Premature Infants (H-37231)

A Randomized Trial of the Use of Human Milk Cream to Decrease Length of Stay in Extremely Premature Infants

At present, widespread use of the human milk-based caloric supplement (cream) has not occurred, particularly in infants with bronchopulmonary dysplasia (BPD), and further data are needed to support its adoption as a standard care practice.

The investigators hypothesize that infants who receive an exclusive human milk (HM)-based diet with the addition of a HM-derived cream caloric supplement (Cream group) will have a shorter length of initial hospital stay compared to infants receiving the standard regimen of an exclusive HM-based diet (Control group). The investigators hypothesize that the effects of the cream caloric supplement will be greater in the subgroup of infants who develop BPD so the relationship will be evaluated between Cream Supplement study group and postmenstrual age (PMA) at discharge and the incidence of BPD.

For study details see Use of Human Milk Cream to Decrease Length of Stay in Extremely Premature Infants.