About the Lab
Obesity serves as a pivotal risk factor for diabetes, fatty liver diseases, cardiovascular disorders, and cancer. Obesity arises from an imbalance between energy intake and expenditure, predominantly orchestrated by the central nervous system (CNS). Our research focuses on the interplay between the central nervous system and systemic energy homeostasis. Using a variety of techniques, including optogenetics, calcium imaging, RNA sequencing, and mouse genetics, we aim to identify the key molecules, cell types, and neural connections that are critical for the regulation of eating behavior and body weight and how these regulatory mechanisms malfunction in conditions like obesity. The ultimate goal is to identify therapeutic targets for combating obesity and metabolic disease.
