Mechanistic Study of Epigenetic Regulation by Polycomb/Trithorax Group Proteins
- Master epigenetic regulators polycomb group (PcG) and trithorax group (TrxG) proteins
- Identification of unknown polycomb- or trithorax-recruiting factors
- Roles of non-coding RNAs
- Hallmark features of polycomb or trithorax-response elements
- Structural biology, cell biology, bioinformatics, comparative genomics, drug discovery
Actin Dynamics in Muscle Contraction and Signal Transduction
- Identification of unknown actin nucleators
- Mechanisms of actin nucleation
- Actin dynamics in muscle contraction and signal transduction
- Structural biology, cell biology, bioinformatics, drug discovery
Mechanisms of Influenza Virus Infection
- Interplay between influenza virus and host factors
- Determinants of human tissue tropism of influenza virus
- Evolution of influenza virus
- Mechanisms of membrane fusion