Rap1 in the VMH regulates glucose homeostasis.
Kentaro Kaneko, Hsiao-Yun Lin, Yukiko Fu, Pradip K Saha, Ana B De la Puente-Gomez, Yong Xu, Kousaku Ohinata, Peter Chen, Alexei Morozov, Makoto Fukuda. JCI insight 2021 Jun 8;6(11):e142545. doi: 10.1172/jci.insight.142545.
Gut-derived GIP activates central Rap1 to impair neural leptin sensitivity during overnutrition.
Kentaro Kaneko, Yukiko Fu, Hsiao-Yun Lin, Elizabeth L Cordonier, Qianxing Mo, Yong Gao, Ting Yao, Jacqueline Naylor, Victor Howard, Kenji Saito, Pingwen Xu, Siyu S Chen, Miao-Hsueh Chen, Yong Xu, Kevin W Williams, Peter Ravn, Makoto Fukuda. The Journal of clinical investigation 2019 Aug 12;129(9):3786-3791. doi: 10.1172/JCI126107
Neuronal Rap1 Regulates Energy Balance, Glucose Homeostasis, and Leptin Actions
Kentaro Kaneko, Pingwen Xu, Elizabeth L. Cordonier, Siyu S. Chen, Amy Ng, Yong Xu, Alexei Morozov, Makoto Fukuda. Cell Reports 2016 Sep 13;16(11):3003-3015. doi: 10.1016/j.celrep.2016.08.039.
