Yeying Huang, R. Taylor Durall, Nhi M. Luong, Hans J. Hertzler, Julianna Huang, Prafulla C. Gokhale, Brittaney A. Leeper, Nicole S. Persky, David E. Root, Praju V. Anekal, Paula D.L.M. Montero Llopis, Clement N. David, Jeffery L. Kutok, Alejandra Raimondi, Karan Saluja, Jia Luo, Cynthia A. Zahnow, Biniam Adane, Kimberly Stegmaier, Catherine E. Hawkins, Christopher Ponne, Quan Le, Geoffrey I. Shapiro, Madeleine E. Lemieux, Kyle P. Eagen*, Christopher A. French*. EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes. Cancer Research (2023) 83, 3956-3973. *Corresponding author
- Highlighted in Cancer Research
R. Taylor Durall, Julianna Huang, Luke Wojenski, Yeying Huang, Prafulla C. Gokhale, Brittaney A. Leeper, Joshua O. Nash, Pedro L. Ballester, Scott Davidson, Adam Shlien, Emmanuel Sotirakis, Fabien Bertaux, Vincent Dubus, Jia Luo, Catherine J. Wu, Derin B. Keskin, Kyle P. Eagen, Geoffrey I. Shapiro, Christopher A. French. The BRD4-NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma. Cancer Research (2023) 83, 3846-3860.
Kyle P. Eagen. BET proteins loop and compartmentalize the 3D genome. Nature Genetics (2022) 54, 370-371.
Ann K. Hogan, Kizhakke M. Sathyan, Alexander B. Willis, Sakshi Khurana, Shashank Srivastava, Ewelina Zasadzińska, Alexander S. Lee, Aaron O. Bailey, Matthew N. Gaynes, Jiehuan Huang, Justin Bodner, Celeste D. Rosencrance, Kelvin A. Wong, Marc A. Morgan, Kyle P. Eagen, Ali Shilatifard, Daniel R. Foltz. UBR7 acts as a histone chaperone for post-nucleosomal histone H3. EMBO Journal (2021) 40, e108307.
Kyle P. Eagen*, Christopher A. French*. Supercharging BRD4 with NUT in Carcinoma. Oncogene (2021) 40, 1396-1408. *Corresponding author
Celeste D. Rosencrance, Haneen N. Ammouri, Qi Yu, Tiffany Ge, Emily J. Rendleman, Stacy A. Marshall, Kyle P. Eagen. Chromatin Hyperacetylation Impacts Chromosome Folding by Forming a Nuclear Subcompartment. Molecular Cell (2020) 78, 112-126.
- Highlighted in Nature Reviews Molecular Cell Biology
Celestia Fang, Zhenjia Wang, Cuijuan Han, Stephanie L. Safgren, Kathryn A. Helmin, Emmalee R. Adelman, Valentina Serafin, Giuseppe Basso, Kyle P. Eagen, Alexandre Gaspar-Maia, Maria E. Figueroa, Benjamin D. Singer, Aakrosh Ratan, Panagiotis Ntziachristos†, Chongzhi Zang†. Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation. Genome Biology (2020) 21, 247.
Tiffany Ge*, Celeste D. Rosencrance*, Kyle P. Eagen. Contact Mapping to Unravel Chromosome Folding. Trends in Biochemical Sciences (2019) 44, 1089-1090. *Equal contributions
Kyle P. Eagen. Principles of Chromosome Architecture Revealed by Hi-C. Trends in Biochemical Sciences (2018) 43, 469-478.
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- Best of Trends Series: Best and most downloaded review published in Trends in Biochemical Sciences in 2018.
- Highlighted in F1000 Prime.
Kyle P. Eagen*, Erez Lieberman Aiden, Roger D. Kornberg*. Polycomb-Mediated Chromatin Loops Revealed by a Sub-kilobase Resolution Chromatin Interaction Map. Proceedings of the National Academy of Sciences of the United States of America (2017) 114, 8764-8769. *Corresponding author
- Highlighted in F1000 Prime.
Shigeki Nagai, Ralph E. Davis, Pierre Jean Mattei, Kyle P. Eagen, Roger D. Kornberg. Chromatin Potentiates Transcription. Proceedings of the National Academy of Sciences of the United States of America (2017) 114, 1536-1541.
Kyle P. Eagen, Tom A. Hartl, Roger D. Kornberg. Stable Chromosome Condensation Revealed by Chromosome Conformation Capture. Cell (2015) 163, 934-946.
- Highlighted in Nature Reviews Molecular Cell Biology, Nature Reviews Genetics, and F1000 Prime.
Ryan W. Lewis, John Mabry, Jason G. Polisar, Kyle P. Eagen, Bruce Ganem, George P. Hess. Dihydropyrimidinone Positive Modulation of Delta Subunit-containing GABAA Receptors, Including an Epilepsy-linked Mutant Variant. Biochemistry (2010) 49, 4841-4851.
Brian A. Kelch, Kyle P. Eagen, F. Pinar Erciyas, Elizabeth L. Humphris, Adam R. Thomason, Shinji Mitsuiki, David A. Agard. Structural and Mechanistic Exploration of Acid Resistance: Kinetic Stability Facilitates Evolution of Extremophilic Behavior. Journal of Molecular Biology (2007) 368, 870-883.
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