Publications

Amano, A. Chaudhury, C. Rodriguez-Aguayo, L. Lu, V. Akhanov, A. Catic, E. Verdin, H. Johnson, F. Stossi, D.A. Sinclair, E. Nakamaru-Ogiso, G. Lopez-Berestein, J.R. Neilson, A. Meeker, M. Finegold, J.A. Baur, and E. Sahin, 2019. Telomere dysfunction induces sirtuin repression that drives telomere-dependent disease. In Press, Cell Metabolism.

Bertolet, N. Kongchan, R. Miller, R.K. Patel, A. Jain, J.M. Choi, A. Saltzman, A. Christenson., S.Y. Jung, A. Malovannaya, A. Grimson, and J.R. Neilson, 2019. Mir-146a 3ʹ pairing specificity is dispensable for proper innate immune function in vivo. Life Sci Alliance. 2019 Feb18;2(1). pii: e201800249. doi: 10.26508/lsa.201800249. PMCID: PMC6379685.

Pal, M. Palmieri, A. Chaudhury, T.J. Klisch, A di Ronza, J.R. Neilson, G.G. Rodney, and M. Sardiello, 2018. Src acts as an essential regulator of amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction. Nature Communications 9(1):4351. PMCID: PMC6195609

L.C. Reineke, S.A. Cheema, J. Dubrulle, and J.R. Neilson, 2018. Chronic starvation induces non-canonical pro-death stress granules. J Cell Sci. 131(19). PMCID: Pending

T.M. Nguyen, E.B. Kabotyanski, Y. Dou, L.C. Reineke, P. Zhang, X. Zhang, A. Malovannaya, S.Y. Jung, Q. Mo, K. Roarty, Y. Chen, B. Zhang, J.R. Neilson, R.E. Lloyd, C.M. Perou, M.J. Ellis, and J.M. Rosen, 2018. FGFR1-activated translation of WNT pathway components with structured 5' UTRs is vulnerable to inhibition of EIF4A-dependent translation initiation. Cancer Res. 2018 Aug 1;78(15):4229-4240. PMCID: Pending

H.J. Park, P. Ji, S. Kim, Z. Xia, B. Rodriguez, L. Li, J. Su, K. Chen., C.P. Masamha, D. Baillat, C.R. Fontes, A.B. Shyu, J.R. Neilson, E.J. Wagner, and W. Li, 2018. 3ʹ UTR shortening represses tumor suppressors in trans by disrupting ceRNA crosstalk. Nature Genetics Jun;50(6):783-789. PMCID: Pending

Yang, N. Kongchan, J.R. Neilson, and K.D. Hirschi, 2017. The atypical genesis and bioavailability of the plant-based small RNA MIR2911: bulking up while breaking down. Mol Nutr Food Res Sep;61(9). PMCID: PMC5583006

Palmieri, R. Pal, H.R. Nelvagal, P. Lotfi, G.R. Stinnett, M.L. Seymour, A. Chaudhury, L. Bajaj, L. Bremner, U. Saleem, D.Y. Tse, D. Sanagasetti, S.M. Wu, J.R. Neilson, F.A. Pereira, R.G. Pautler, G.G. Rodney, J.D. Cooper, and M. Sardiello, 2017. mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases. Nature Communications 8:14338. PMCID: PMC5303831

Chaudhury, S. Cheema, J.M. Fachini, N. Kongchan, G. Lu, L.M. Simon, T. Wang, S. Mao, D.G. Rosen, M.M. Ittmann, S.G. Hilsenbeck, C.A. Shaw, and J.R. Neilson, 2016. CELF1 is a central node in post-transcriptional regulatory programs underlying EMT. Nature Communications 7:13362. PMCID: PMC5121338

Tajhya, X. Hu, M.R. Tanner, R. Huq, N. Kongchan, J.R. Neilson, G.G. Rodney, F.T. Horrigan, L.T. Timchenko, and C. Beeton, 2016. KCa1.1 channels are crucial for the proliferation, migration and differentiation of human myoblasts. Cell Death Dis. 7(10):e2426. PMCID: PMC5133989

Xu, A. Chaudhury, M. Zhang, B. Savoldo, L. Metelitsa, J. Rodgers, J. Yustein, J.R. Neilson, and G. Dotti, 2016. Glycolysis determines dichotomous regulation of T cell subsets in hypoxia. Journal of Clinical Investigation 126(7):2678-88. PMCID: PMC4922684

R.G. Domingues, I. Lago-Baldaia, I.P. Castro, J.M. Fachini, D. Drpic, N. Lopes, T. Henriques, J.R. Neilson, A.M. Carmo, and A. Moreira, 2016. CD5 expression is regulated during T cell activation by PTB-dependent alternative polyadenylation and miR-204. European Journal of Immunology doi: 10.1002/eji.201545663

Pal, L. Bajaj, J. Sharma, M. Palmieri, A. Di Ronza, P. Lotfi, A. Chaudhury, J. Neilson, M. Sardiello and G.G. Rodney, 2016. NADPH oxidase promotes Parkinsonian phenotypes by impairing autophagic flux in an mTORC1-independent fashion. Scientific Reports 6:22866. doi: 10.1038/srep22866

J.R. Neilson and L.C. Reineke, 2019. Differences between acute and chronic stress granules, and how these differences may impact function in human disease. Biochemical Pharmacology pii: S0006-2952(18)30430-1. doi: 10.1016/j.bcp.2018.10.009

Chaudhury and J.R. Neilson, 2016. Use of the pBUTR reporter system for scalable analysis of 3' UTR-mediated regulation. Methods in Molecular Biology 1358:109-28