Email

weisheng.lu@bcm.edu

Positions

Postdoctoral Associate

Pediatrics - Nutrition
Baylor College of Medicine
Houston, US

Senior Scientist

Analysis Science
Shanghai Hansoh Biomedical R&D Inc.
Shanghai, Shanghai China
Leading the project of novel anti-tumor Antibody-Drug Conjugates (ADCs) activity measurement methods development.

Addresses

Children's Nutrition Research Center (Office)

1100 BATES
Room 8062
Houston, TX 77030
United States

Children's Nutrition Research Center (Lab)

1100 BATES
Room 8052
Houston, TX 77030
United States

Education

PharmD from China Pharmaceutical University

06/2021 - Nanjing, Jiangsu China

BS from China Pharmaceutical Univeristy

06/2015 - Nanjing, Jiangsu China

Websites

Selected Publications

• Kentaro Kaneko, Weisheng Lu, Yong Xu, Alexei Morozov, Makoto Fukuda "The small GTPase Rap1 in POMC neurons regulates leptin actions and glucose metabolism." 2025 Feb 28;102117 Pubmed PMID: 40024570
• Lu W, Tian H, Qian P, Li Y, Wang Y, Ge Y, Sai W, Gao X, Yao W "An orally available hypoglycaemic peptide taken up by caveolae transcytosis displays improved hypoglycaemic effects and body weight control in db/db mice." Br J Pharmacol. 2020 Apr 15;177(15):3473-3488. Pubmed PMID: 32293707
• Ma T, Lu W, Wang Y, Qian P, Tian H, Gao X, Yao W "An oral GLP-1 and GIP dual receptor agonist improves metabolic disorders in high fat-fed mice." Eur J Pharmacol. 2022 Jan 5;914(174635) Pubmed PMID: 34800466
• Qian P, Tian H, Wang YK, Lu W, Li Y, Ma T, Gao X, Yao W "A novel oral glucagon-like peptide 1 receptor agonist protects against diabetic cardiomyopathy via alleviating cardiac lipotoxicity induced mitochondria dysfunction." Biochem Pharmacol. 2020 Dec;182(114209) Pubmed PMID: 32860826

Intellectual Property

Oral hypoglycemic peptide, fatty acid derivative and use thereof

Design Patent #WO2021027762A1 (Approved)

Provided in the present invention are an oral hypoglycemic polypeptide, fatty acid modified derivatives thereof, and uses of the polypeptide and the fatty acid modified derivatives thereof.

Co Inventors: GAO Xiangdong, TIAN Hong, LU Weisheng, YAO Wenbing, SAI Wenbo

Languages

Chinese (Mandarin), Japanese