Timothy Baker, M.D.

Assistant Professor

Email

timothyb@bcm.edu

Positions

Assistant Professor: Psychiatry & Behav Sciences
Baylor College of Medicine
Houston, TX, US

Addresses

Veterans Affairs Medical Centr (Office): Room: VAMC-PSYSRV
Houston, TX, 77030
United States

Education

Advanced Training from University Of Texas Health Science Center Affiliate Hospitals: 01/1989 - Houston, TX, United States

M.D. from University Of Texas Medical School At Houston: 01/1989 - Houston, TX, United States

B.S. from Tulane University: 01/1984 - New Orleans, LA, United States

Certifications

Board Certified: American Board of Psychiatry and Neurology

Websites

VIICTR Publications List

Selected Publications

Baker T, Riker WF, Zeldes G. " A benzodiazepine-anticholinergic drug synergism in the prevention of stress-induced gastric mucosal erosion in mice. " J Clin Pharmacol. ; 19 (8) : 409-14.
Pubmed PMID: 314947.
Ji Y, Marinescu DC, Zhang W, Zhang X, Yan X, Baker TS. " A model-based parallel origin and orientation refinement algorithm for cryoTEM and its application to the study of virus structures. " J. Struct. Biol.. 2006 Apr ; 154 (1) : 41293.
Pubmed PMID: 16459100.
Kong Y, Zhang X, Baker TS, Ma J. " A Structural-informatics approach for tracing beta-sheets: building pseudo-C(alpha) traces for beta-strands in intermediate-resolution density maps. " J. Mol. Biol.. 2004 May 21; 339 (1) : 117-30.
Pubmed PMID: 15123425.
Baker TS, Eisenberg D, Eiserling FA, Weissman L. " The structure of form I crystals of D-ribulose-1,5-diphosphate carboxylase. " J. Mol. Biol.. 1975 Feb 5; 91 (4) : 391-9.
Pubmed PMID: 1152035.
Kim J, Zhang X, Centonze VE, Bowman VD, Noble S, Baker TS, Nibert ML. " The hydrophilic amino-terminal arm of reovirus core shell protein lambda1 is dispensable for particle assembly. " J. Virol.. 2002 Dec ; 76 (23) : 12211-22.
Pubmed PMID: 12414960.
Yan X, Yu Z, Zhang P, Battisti AJ, Holdaway HA, Chipman PR, Bajaj C, Bergoin M, Rossmann MG, Baker TS. " The capsid proteins of a large, icosahedral dsDNA virus. " J. Mol. Biol.. 2009 Jan 30; 385 (4) : 1287-99.
Pubmed PMID: 19027752.
Speir JA, Munshi S, Wang G, Baker TS, Johnson JE. " Structures of the native and swollen forms of cowpea chlorotic mottle virus determined by X-ray crystallography and cryo-electron microscopy. " Structure. 1995 Jan 15; 3 (1) : 63-78.
Pubmed PMID: 7743132.
Kumar A, Reddy VS, Yusibov V, Chipman PR, Hata Y, Fita I, Fukuyama K, Rossmann MG, Loesch-Fries LS, Baker TS, Johnson JE. " The structure of alfalfa mosaic virus capsid protein assembled as a T=1 icosahedral particle at 4.0-A resolution. " J. Virol.. 1997 Oct ; 71 (10) : 7911-6.
Pubmed PMID: 9311881.
Baker TS, Amos LA. " Structure of the tubulin dimer in zinc-induced sheets. " J. Mol. Biol.. 1978 Jul 25; 123 (1) : 89-106.
Pubmed PMID: 682196.
Zhang X, Tang J, Walker SB, O'Hara D, Nibert ML, Duncan R, Baker TS. " Structure of avian orthoreovirus virion by electron cryomicroscopy and image reconstruction. " Virology. 2005 Dec 5; 343 (1) : 25-35.
Pubmed PMID: 16153672.
Padron E, Bowman V, Kaludov N, Govindasamy L, Levy H, Nick P, McKenna R, Muzyczka N, Chiorini JA, Baker TS, Agbandje-McKenna M. " Structure of adeno-associated virus type 4. " J. Virol.. 2005 Apr ; 79 (8) : 5047-58.
Pubmed PMID: 15795290.
Liu H, Smith TJ, Lee WM, Mosser AG, Rueckert RR, Olson NH, Cheng RH, Baker TS. " Structure determination of an Fab fragment that neutralizes human rhinovirus 14 and analysis of the Fab-virus complex. " J. Mol. Biol.. 1994 Jul 8; 240 (2) : 127-37.
Pubmed PMID: 8027997.
Bernal RA, Hafenstein S, Olson NH, Bowman VD, Chipman PR, Baker TS, Fane BA, Rossmann MG. " Structural studies of bacteriophage alpha3 assembly. " J. Mol. Biol.. 2003 Jan 3; 325 (1) : 41602.
Pubmed PMID: 12473449.
Zhang X, Walker SB, Chipman PR, Nibert ML, Baker TS. " Reovirus polymerase lambda 3 localized by cryo-electron microscopy of virions at a resolution of 7.6 A. " Nat. Struct. Biol.. 2003 Dec ; 10 (12) : 1011-8.
Pubmed PMID: 14608373.
Dimattia MA, Nam HJ, Van Vliet K, Mitchell M, Bennett A, Gurda BL, McKenna R, Olson NH, Sinkovits RS, Potter M, Byrne BJ, Aslanidi G, Zolotukhin S, Muzyczka N, Baker TS, Agbandje-McKenna M. " Structural insight into the unique properties of adeno-associated virus serotype 9. " J. Virol.. 2012 Jun ; 86 (12) : 6947-58.
Pubmed PMID: 22496238.
Odegard AL, Chandran K, Zhang X, Parker JS, Baker TS, Nibert ML. " Putative autocleavage of outer capsid protein micro1, allowing release of myristoylated peptide micro1N during particle uncoating, is critical for cell entry by reovirus. " J. Virol.. 2004 Aug ; 78 (16) : 8732-45.
Pubmed PMID: 15280481.
Wetter DW, Kenford SL, Welsch SK, Smith SS, Fouladi RT, Fiore MC, Baker TB. " Prevalence and predictors of transitions in smoking behavior among college students. " Health Psychol. 2004 Mar ; 23 (2) : 168-77.
Pubmed PMID: 15008662.
Bakht FR, Kirshon B, Baker T, Cotton DB. " Postpartum cardiovascular complications after bromocriptine and cocaine use. " Am. J. Obstet. Gynecol.. 1990 Apr ; 162 (4) : 1065-6.
Pubmed PMID: 2327446.
Miller LG, Bakht FR, Baker T, Kirshon B. " Possible cocaine predisposition to adverse cerebrovascular and cardiovascular sequelae of bromocriptine administered postpartum. " J Clin Pharmacol. 1989 Sep ; 29 (9) : 781-5.
Pubmed PMID: 2808744.
Stoops JK, Cheng RH, Yazdi MA, Maeng CY, Schroeter JP, Klueppelberg U, Kolodziej SJ, Baker TS, Reed LJ. " On the unique structural organization of the Saccharomyces cerevisiae pyruvate dehydrogenase complex. " J. Biol. Chem.. 1997 Feb 28; 272 (9) : 5757-64.
Pubmed PMID: 9038189.
Belnap DM, Kumar A, Folk JT, Smith TJ, Baker TS. " Low-resolution density maps from atomic models: how stepping back" can be a step "forward"." " J. Struct. Biol.. ; 125 (41308) : 166-75.
Pubmed PMID: 10222272.
Luongo CL, Zhang X, Walker SB, Chen Y, Broering TJ, Farsetta DL, Bowman VD, Baker TS, Nibert ML. " Loss of activities for mRNA synthesis accompanies loss of lambda2 spikes from reovirus cores: an effect of lambda2 on lambda1 shell structure. " Virology. 2002 Apr 25; 296 (1) : 24-38.
Pubmed PMID: 12036315.
Levy HC, Bowman VD, Govindasamy L, McKenna R, Nash K, Warrington K, Chen W, Muzyczka N, Yan X, Baker TS, Agbandje-McKenna M. " Heparin binding induces conformational changes in Adeno-associated virus serotype 2. " J. Struct. Biol.. 2009 Mar ; 165 (3) : 146-56.
Pubmed PMID: 19121398.
Baker TS, Sosinsky GE, Caspar DL, Gall C, Goodenough DA. " Gap junction structures. VII. Analysis of connexon images obtained with cationic and anionic negative stains. " J. Mol. Biol.. 1985 Jul 5; 184 (1) : 81-98.
Pubmed PMID: 2411939.
Cheng RH, Caston JR, Wang GJ, Gu F, Smith TJ, Baker TS, Bozarth RF, Trus BL, Cheng N, Wickner RB. " Fungal virus capsids, cytoplasmic compartments for the replication of double-stranded RNA, formed as icosahedral shells of asymmetric Gag dimers. " J. Mol. Biol.. 1994 Dec 2; 244 (3) : 255-8.
Pubmed PMID: 7966336.
Zhang X, Ji Y, Zhang L, Harrison SC, Marinescu DC, Nibert ML, Baker TS. " Features of reovirus outer capsid protein mu1 revealed by electron cryomicroscopy and image reconstruction of the virion at 7.0 Angstrom resolution. " Structure. 2005 Oct ; 13 (10) : 1545-57.
Pubmed PMID: 16216585.
Tang J, Jose J, Chipman P, Zhang W, Kuhn RJ, Baker TS. " Molecular Links between the E2 Envelope Glycoprotein and Nucleocapsid Core in Sindbis Virus. " J. Mol. Biol.. 2011 Dec 2; 414 (3) : 442-59.
Pubmed PMID: 22001018.
Tang J, Lee KK, Bothner B, Baker TS, Yeager M, Johnson JE. " Dynamics and stability in maturation of a T=4 virus. " J. Mol. Biol.. 2009 Sep 25; 392 (3) : 803-12.
Pubmed PMID: 19627990.
Belnap DM, Olson NH, Cladel NM, Newcomb WW, Brown JC, Kreider JW, Christensen ND, Baker TS. " Conserved features in papillomavirus and polyomavirus capsids. " J. Mol. Biol.. 1996 Jun 7; 259 (2) : 249-63.
Pubmed PMID: 8656427.
Chandran K, Zhang X, Olson NH, Walker SB, Chappell JD, Dermody TS, Baker TS, Nibert ML. " Complete in vitro assembly of the reovirus outer capsid produces highly infectious particles suitable for genetic studies of the receptor-binding protein. " J. Virol.. 2001 Jun ; 75 (11) : 5335-42.
Pubmed PMID: 11333914.
Patterson TA, Zhang Z, Baker T, Johnson LL, Friedman DI, Court DL. " Bacteriophage lambda N-dependent transcription antitermination. Competition for an RNA site may regulate antitermination. " J. Mol. Biol.. 1994 Feb 11; 236 (1) : 217-28.
Pubmed PMID: 8107107.
Pan J, Dong L, Lin L, Ochoa WF, Sinkovits RS, Havens WM, Nibert ML, Baker TS, Ghabrial SA, Tao YJ. " Atomic structure reveals the unique capsid organization of a dsRNA virus. " Proc. Natl. Acad. Sci. U.S.A.. 2009 Mar 17; 106 (11) : 4225-30.
Pubmed PMID: 19246376.
Bowman VD, Chase ES, Franz AW, Chipman PR, Zhang X, Perry KL, Baker TS, Smith TJ. " An antibody to the putative aphid recognition site on cucumber mosaic virus recognizes pentons but not hexons. " J. Virol.. 2002 Dec ; 76 (23) : 12250-8.
Pubmed PMID: 12414964.