Email

shixiah@bcm.edu

Positions

Professor

Mol & Cell Biology
Baylor College of Medicine

Director, Antibody-Based Proteomics Core

Advanced Technology Cores
Baylor College of Medicine
Houston, Texas United States

Professor

Education, Innovation & Technology
Baylor College of Medicine

Faculty Senator

Baylor College of Medicine

Chair, Research Subcommittee

Inclusion and Excellence Council
Baylor College of Medicine

Member

Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine

DEI Council Member

Association of Biomolecular Resource Facilities

Program Director

Baylor College of Medicine

Baylor College of Medicine Biotechnology Research Incubator for Teachers and Students (BCM-BRITE) BCM-BRITE High School Student Biotechnology Research Symposium: BCM-BRITE Biotechnology Research High School Student Symposium is an opportunity for students to organize their research work into a structured abstract and present their research in a poster or PowerPoint format to their peers and mentors. The abstracts presented in the 2022 symposium are by high school students who conducted biotechnology research projects at Baylor College of Medicine, MD Anderson Cancer Center, Texas Southern University, and New York University. BCM-BRITE Biotechnology Research Teacher's Training Workshop: BCM-BRITE Teacher’s Workshop trains science teachers from middle and high schools in foundational scientific research approaches, expose them to cutting-edge biotechnologies and provide mentorship opportunities by scientists and STEMM specialists to translate their training into direct classroom experiences for students. Specifically, the program is centered around a two/three-week hands-on technology-research immersion program for the teachers to work side-by-side with scientists in the laboratory to solve real-world problems. At the same time, STEMM education specialists work with the teachers to develop a lesson plan for the teachers’ grades and classrooms. The program includes an editor of BioEd Online (https://www.bioedonline.org/) to help ensure that the lesson plans meet the content quality and format requirements for publication on this public education platform thus benefiting teachers and students in Texas, the US, and around the world.

Education

PhD from Michigan State University

East Lansing, Michigan United States

Genetics

Postdoctoral Fellowship at National Cancer Institute

Bethesda, Maryland United States

Postdoctoral Fellowship at Memorial Sloan-Kettering Cancer Center

New York, New York United States

MS from Yangzhou University

Yangzhou, Jiangsu China, People's Rep

Infectious Disease & Preventive Veterinary Medicine

BS from Hunan Agricultural University

Changsha, Hunan China, People's Rep

Veterinary Medicine

Professional Statement

Developing high-throughput antibody-based proteomic platforms for protein biomarker discovery and validation, especially for low abundance regulatory proteins and their activation states such as phosphorylation and histone translational modifications.
Combining my advance technology expertise and passion in education to build biotechnology education programs with a focus on diversity and inclusion.

Websites

Selected Publications

• Huang S, Li Y, Chen Y, Podsypanina K, Chamorro M, Olshen AB, Desai KV, Tann A, Petersen D, Green JE, Varmus HE "Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice.." Genome Biol.. 2005;6(10):R84. Pubmed PMID: 16207355
• Huang S, Flanders KC, Roberts AB "Characterization of the mouse Smad1 gene and its expression pattern in adult mouse tissues.." Gene. 2000 Nov 27;258(41276):43-53. Pubmed PMID: 11111041
• Li Y, Welm B, Podsypanina K, Huang S, Chamorro M, Zhang X, Rowlands T, Egeblad M, Cowin P, Werb Z, Tan LK, Rosen JM, Varmus HE "Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells.." Proc. Natl. Acad. Sci. U.S.A.. 2003 Dec 23;100(26):15853-8. Pubmed PMID: 14668450
• Lu, H.-Y., Xiong, j., Perera, D. N., Rajapakshe, K., Wang, X., Costello M., Holloway K. R., Ramos, C., Grimm, S. L., Wulfkuhle, J., Coarfa, C., Edwards, D. P., Zhu, M. X., and Huang, S. "High-throughput Evaluation of Metabolic Activities Using Reverse Phase Protein Array (RPPA) Technology." Book chapter in: Tong, Q., 1st ed. Neuronal Signaling in Metabolism. 2021 Jun;1st Edition:25.