Email

remoses@bcm.edu

Positions

Professor

Mol & Cell Biology-O'Malley
Baylor College of Medicine
Houston, TX US

Member

Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States

Education

M.D. from Johns Hopkins University School Of Medicine

01/1966 - Baltimore, MD United States

A.B. from Houghton College

01/1962 - Houghton, NY United States

Advanced Training from Johns Hopkins Hospital

01/1967 - Baltimore, MD United States

Honors & Awards

Faculty Excellence Award

Fulbright & Jaworski

Research Award

NATO

Fellow

Fogarty

Genetics Study Section

National Institutes of Health

Special Fellow

National Institutes of Health

Magna cum laude

A.B. degree

Houghton College

Professional Interests

• Genome Stability, Applied Metabolism, Heritable DNA Repair Defects

Professional Statement

My career has focused on the genome, its stability and maintenance, and DNA repair in relation to cancer, aging and inherited diseases of DNA processing. My studies have been funded continuously for 40 years by several agencies, including the National Institute of Aging, the National Institute of General Medical Sciences, the National Cancer Institute and the National Heart, Lung and Blood Institute. For the past 15 years my work has concentrated on Fanconi Anemia, a cancer-prone inherited defect in genome stability. During that interval the team I led at OHSU isolated the FANCD2 gene, and tracked its mono-ubiquitination and defined its interaction with FANCI to form the active dyad required for DNA inter strand crosslink repair. My experience in genome stability, genomics, clinical genetics, clinical laboratory interpretations, and aging will allow me to contribute to the proposed work.

Websites