Email

reza.ardehali@bcm.edu

Positions

Professor

Medicine-Cardiology
Baylor College of Medicine
Houston, Texas United States

Addresses

Texas Heart Institute (Office)

6770 BERTNER AVENUE
5th Floor
Houston, TX 77030
United States

Education

PhD from University of Utah

06/1998 - Salt Lake City, Utah United States

MD from Emory University School of Medicine

06/2002 - Atlanta, Georgia United States

Residency at The Johns Hopkins Hospital

07/2003 - Baltimore, Maryland United States

Fellowship at Stanford University Medical Center

07/2010 - Stanford, California United States

Certifications

Board Certified - Internal Medicine

American Board of Internal Medicine

Board Certified - Cardiovascular Disease

American Board of Internal Medicine

Honors & Awards

NIH Director's New Innovator Award (2016)

Douglas P. Zipes Distinguished Young Scientist Award (2017)

American College of Cardiology

Elected as Fellow, American Heart Association (2019)

Elected to American Society of Clinical Investigation (2019)

ISHR-NAS President Award (2021)

Professional Interests

• Advanced Heart Failure
• Mechanical Circulatory Support
• Transplantation General Cardiology

Professional Statement

Dr. Ardehali is a physician-scientist in the section of Cardiology at Baylor College of Medicine. He has been in practice for more than 15 years, treating patients with advanced heart failure who require medical or invasive therapies such as heart transplantation or mechanical circulatory support. Realizing the limited therapeutic options for patients with heart failure, Dr. Ardehali’s group has been performing research on stem cells as a potential source to repair the heart. His research team recently developed an efficient method to generate subtypes of cardiomyocytes from differentiating human pluripotent stem cells and started preclinical transplantation studies in large animal models. His lab was the first to demonstrate the proliferative capacity of cardiomyocytes during neonatal period and after injury, the first to discover the embryonic origin of cardiac fibroblasts and established the fundamental role of pericytes in cardiac fibrosis. In addition to many honors and awards, he has had NIH funding throughout his career and has mentored many trainees who started their independent careers.

Websites

Selected Publications

• Quijada P, Park S, Zhao P, Kolluri KS, Wong D, Shih KD, Fang K, Pezhouman A, Wang L, Daraei A, Tran MD, Rathbun EM, Burgos Villar KN, Garcia-Hernandez ML, Pham TT, Lowenstein CJ, Iruela-Arispe ML, Carmichael ST, Small EM, Ardehali R. "Cardiac pericytes mediate the remodeling response to myocardial infarction." J Clin Invest. 2023 May 15;133(10):e162188. Pubmed PMID: 37183820
• Pezhouman A, Engel J, Nguyen NB, Skelton RJ, Gilmore WB, Qiao R, Sahoo D, Zhao P, Elliott DA, Ardehali R. "Isolation and characterization of hESC-derived heart field- specific cardiomyocytes unravels new insights into their transcriptional and electrophysiological profiles." Cardiovasc Res. 2022 Feb 21;118(3):828-843. Pubmed PMID: 33744937
• Pham TTD, Park S, Kolluri K, Kawaguchi R, Wang L, Tran D, Zhao P, Carmichael ST, Ardehali R. "Heart and Brain Pericytes Exhibit a Pro-Fibrotic Response After Vascular Injury." Circ Res. 2021 Sep 17;129(7):e141-e143.. Pubmed PMID: 34399580
• Sereti KI, Nguyen NB, Kamran P, Zhao P, Ranjbarvaziri S, Park S, Sabri S, Engel J, Sung K, Kulkami RP, Ding Y, Hsiai TK, Plath K, Ernst J, Sahoo D, Mikkola H, Iruela- Arispe L, Ardehali R. "Analysis of cardiomyocyte clonal expansion during mouse heart development and injury." Nature Commun. 2018 Feb 21;9:754. Pubmed PMID: 29467410

Languages

Farsi