Qin Feng
Picture
Qin Feng
Assistant Professor
Positions
- Assistant Professor
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Mol & Cell Biology-Mol.Regulation
Baylor College of Medicine
Houston, TX US
- Member
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Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States
Addresses
- Laboratory (Lab)
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BCM-Michael DeBakey Center
Room: BCMM-M713
Houston, TX 77030
United States
Phone: (713) 798-6247
qfeng@bcm.edu
Education
- Advanced Training from Baylor College Of Medicine
- 01/2009 - Houston, TX United States
- Ph.D. from University Of North Carolina At Chapel Hill
- 01/2003 - Chapel Hill, NC United States
Professional Interests
- Epigenetic Regulation of gene expression
Websites
Selected Publications
- Zhang Z, Nikolai BC, Gates LA, Jung SY, Siwak EB, He B, Rice AP, O'Malley BW, Feng Q "Crosslink between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency." Nucleic Acids Res. 2017 Sep 19;45:9348. Pubmed PMID: 28637181
- Nikolai BC, Feng Q "HIV latency gets a new histone mark." Cell Host Microbe. 2017 May 10;21:549. Pubmed PMID: 28494231
- Zhang Z, Lanz RB, Xiao L, Wang L, Hartig SM, Ittmann MM, Feng Q, He B "The tumor suppressive miR-200b subfamily is an ERG target gene in human prostate tumors." Oncotarget. 2016 May 13; Pubmed PMID: 27191272
- Feng Q, Zhang Z, Shea MJ, Creighton CJ, Coarfa C, Hilsenbeck SG, Lanz R, He B, Wang L, Fu X, Nardone A, Song Y, Bradner J, Mitsiades N, Mitsiades CS, Osborne CK, Schiff R, O'Malley BW "An epigenomic approach to therapy for tamoxifen-resistant breast cancer." Cell research. 2014 Jul;24(7):809-19. Pubmed PMID: 24874954
- Feng Q, He B, Jung SY, Song Y, Qin J, Tsai SY, Tsai MJ, O'Malley BW "Biochemical control of CARM1 enzymatic activity by phosphorylation." J Biol Chem. 2009 Dec 25;284(52):36167-74. Pubmed PMID: 19843527
- Wu RC, Feng Q, Lonard DM, O'Malley BW "SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock." Cell. 2007 Jun 15;129(6):1125-40. Pubmed PMID: 17574025
- Feng Q, Yi P, Wong J, O'Malley BW "Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly.." Mol. Cell. Biol.. 2006 Nov;26(21):7846-57. Pubmed PMID: 16923966
- Yu C, York B, Wang S, Feng Q, Xu J, O'Malley BW "An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response.." Mol. Cell. 2007 Mar 9;25(5):765-78. Pubmed PMID: 17349961
- Yi P, Feng Q, Amazit L, Lonard DM, Tsai SY, Tsai MJ, O'Malley BW "Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1.." Mol. Cell. 2008 Feb 29;29(4):465-76. Pubmed PMID: 18313384
- Li X, Lonard DM, Jung SY, Malovannaya A, Feng Q, Qin J, Tsai SY, Tsai MJ, O'Malley BW "The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome.." Cell. 2006 Jan 27;124(2):381-92. Pubmed PMID: 16439211
- Okada Y, Feng Q, Lin Y, Jiang Q, Li Y, Coffield VM, Su L, Xu G, Zhang Y "hDOT1L links histone methylation to leukemogenesis." Cell. 2005 Apr 22;121(2):167-78. Pubmed PMID: 15851025
- Feng Q, Wang H, Ng HH, Erdjument-Bromage H, Tempst P, Struhl K, Zhang Y "Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain." Current Biology. 2002 Jun 25;12(12):1052-8. Pubmed PMID: 12123582
- Min J, Feng Q, Li Z, Zhang Y, Xu RM "Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase." Cell. 2003 May 7;112(5):711-23. Pubmed PMID: 12628190
- Feng Q, Zhang Y "The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes.." Genes & development. 2001 Apr 1;15(7):827-32. Pubmed PMID: 11297506
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