Qian Ma

Postdoctoral Associate

Email

qian.ma@bcm.edu

Positions

Postdoctoral Associate: Ophthalmology
Baylor College of Medicine

Education

BS from Southwest University: 06/2015 - Chongqing, China; Veterinary Medicine

PhD from Peking University: 07/2017 - Beijing, China; Translational Medicine

Websites

PubMed

Google Scholar

Selected Publications

Shi X, Ma Q, Huo Y, Su Y. "5-Aminoimidazole-4-carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase promotes pulmonary arterial smooth muscle cell proliferation via the Ras signaling pathway." Am J Physiol Cell Physiol. 2024 Aug 12; Pubmed PMID: 39129491
Xu J, Liu Z, Yang Q, Ma Q, Zhou Y, Cai Y, Zhao D, Zhao G, Lu T, Ouyang K, Hong M, Kim HW, Shi H, Zhang J, Fulton D, Miller C, Malhotra R, Weintraub NL, Huo Y. "Adenosine kinase inhibition protects mice from abdominal aortic aneurysm via epigenetic modulation of VSMC inflammation." Cardiovasc Res. 2024 Sep 2; Pubmed PMID: 38722818
Ma Q, Yang Q, Xu J, Zhang X, Kim D, Liu Z, Da Q, Mao X, Zhou Y, Cai Y, Pareek V, Kim HW, Wu G, Dong Z, Song WL, Gan L, Zhang C, Hong M, Benkovic SJ, Weintraub NL, Fulton D Jr, Asara JM, Ben-Sahra I, Huo Y. "ATIC-Associated De Novo Purine Synthesis Is Critically Involved in Proliferative Arterial Disease." Circulation. 2022 Nov 8; Pubmed PMID: 36073366
Cai Y, Zhou Y, Yang Q, Xu J, Da Q, Ma Q, Zhao D, Lu T, Kim HW, Fulton D, Jiang X, Weintraub NL, Dong K, Xu S, Hong M, Liu Z, Huo Y "Blockade of endothelial adenosine receptor 2 A suppresses atherosclerosis in vivo through inhibiting CREB-ALK5-mediated endothelial to mesenchymal transition." Pharmacol Res. 2024 Mar 23; Pubmed PMID: 38522762

Yang Q, Ma Q, Xu J, Liu Z, Mao X, Zhou Y, Cai Y, Da Q, Hong M, Weintraub NL, Fulton DJ, Belin de Chantemèle EJ, Huo Y "Endothelial AMPKα1/PRKAA1 exacerbates inflammation in HFD-fed mice." Br J Pharmacol. 2021 Dec 7; Pubmed PMID: 34796475
ct Liu Z, Xu J, Ma Q, Zhang X, Yang Q, Wang L, Cao Y, Xu Z, Tawfik A, Sun Y, Weintraub NL, Fulton DJ, Hong M, Dong Z, Smith LEH, Caldwell RB, Sodhi A, Huo Y "Glycolysis links reciprocal activation of myeloid cells and endothelial cells in the retinal angiogenic niche." Sci Transl Med. 2020 Aug 5; Pubmed PMID: 32759274
Yang Q, Cai Y, Ma Q, Xiong A, Xu P, Zhang Z, Xu J, Zhou Y, Liu Z, Zhao D, Asara J, Li W, Shi H, Caldwell RB, Sodhi A, Huo Y. "Inactivation of adenosine receptor 2A suppresses endothelial-to-mesenchymal transition and inhibits subretinal fibrosis in mice." Sci Transl Med. 2024 Mar 6; Pubmed PMID: 38446902
Singla B, Lin HP, Ahn W, Xu J, Ma Q, Sghayyer M, Dong K, Cherian-Shaw M, Zhou J, Huo Y, White J, Csányi G "Loss of myeloid cell-specific SIRPα, but not CD47, attenuates inflammation and suppresses atherosclerosis." Cardiovasc Res. 2022 Dec 9; Pubmed PMID: 34940829
Bordan Z, Batori RK, Haigh S, Li X, Meadows ML, Brown ZL, West MA, Dong K, Han W, Su Y, Ma Q, Huo Y, Zhou J, Abdelbary M, Sullivan JC, Weintraub NL, Stepp DW, Chen F, Barman SA, Fulton DJR "PDZ-Binding Kinase, a Novel Regulator of Vascular Remodeling in Pulmonary Arterial Hypertension." Circulation. 2024 Jul 30; Pubmed PMID: 38682326
Yang Q, Ma Q, Xu J, Liu Z, Zou J, Shen J, Zhou Y, Da Q, Mao X, Lu S, Fulton DJ, Weintraub NL, Bagi Z, Hong M, Huo Y. "Prkaa1 Metabolically Regulates Monocyte/Macrophage Recruitment and Viability in Diet-Induced Murine Metabolic Disorders." Front Cell Dev Biol. 2020 Aug; Pubmed PMID: 33511118
Yang Q, Xu J, Ma Q, Liu Z, Sudhahar V, Cao Y, Wang L, Zeng X, Zhou Y, Zhang M, Xu Y, Wang Y, Weintraub NL, Zhang C, Fukai T, Wu C, Huang L, Han Z, Wang T, Fulton DJ, Hong M, Huo Y "PRKAA1/AMPKα1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis." Nat Commun. 2018 Nov 7; Pubmed PMID: 30405100
Ma Q, Yang Q, Xu J, Sellers HG, Brown ZL, Liu Z, Bordan Z, Shi X, Zhao D, Cai Y, Pareek V, Zhang C, Wu G, Dong Z, Verin AD, Gan L, Du Q, Benkovic SJ, Xu S, Asara JM, Ben-Sahra I, Barman S, Su Y, Fulton DJR, Huo Y. "Purine synthesis suppression reduces the development and progression of pulmonary hypertension in rodent models." Eur Heart J.. 2023 Apr 7; Pubmed PMID: 36721994
Liu Z, Shi H, Xu J, Yang Q, Ma Q, Mao X, Xu Z, Zhou Y, Da Q, Cai Y, Fulton DJ, Dong Z, Sodhi A, Caldwell RB, Huo Y "Single-cell transcriptome analyses reveal microglia types associated with proliferative retinopathy." JCI Insight. 2022 Dec 8; Pubmed PMID: 36264636
Liu Z, Mao X, Yang Q, Zhang X, Xu J, Ma Q, Zhou Y, Da Q, Cai Y, Sopeyin A, Dong Z, Hong M, Caldwell RB, Sodhi A, Huo Y "Suppression of myeloid PFKFB3-driven glycolysis protects mice from choroidal neovascularization." Br J Pharmacol. 2022 Nov; Pubmed PMID: 35830274