Oluyinka Olutoye, M.D., Ph.D.
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Positions
- Professor of Surgery
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Division of Pediatric Surgery
Baylor College of Medicine
- Co-Director, Texas Children's Fetal Center
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Texas Children's Hospital
- Professor
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Pediatrics
Baylor College of Medicine
- Professor
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Obstetrics and Gynecology
Baylor College of Medicine
- Faculty Senator
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Baylor College of Medicine
Houston, Texas United States
- Chair, Faculty Senate
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Baylor College of Medicine
United States
Addresses
- Texas Children's Fetal Center (Clinic)
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Texas Children's Pavilion for Women
6651 Main Street
Houston, TX 77030
United States
Phone: (832) 822-3135
http://women.texaschildrens.org/program/texas-children%E2%80%99s-fetal-center
- Texas Children's Hospital (Clinic)
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Mark A. Wallace Tower
6701 Fannin Street
Houston, TX 77030
United States
Phone: (832) 822-3135
Pediatric Surgery
Education
- Postdoctoral Fellowship at Children's Hospital Of Philadelphia
- 01/1999 - Philadelphia, PA United States
- Fetal Surgery
- Clinical Fellowship at Children's Hospital Of Philadelphia
- 01/2001 - Philadelphia, PA United States
- Pediatric, General, Fetal and Thoracic Surgery
- Residency at Medical College Of Virginia Hospitals
- 01/1998 - Richmond, VA United States
- General Surgery
- Internship at Howard University Hospital
- 06/1991 - Washington, DC United States
- Pediatrics
- Ph.D. from Virginia Commonwealth University
- 01/1996 - Richmond, VA United States
- MBChB from Obafemi Awolowo University, Nigeria
- 12/1988 - Ile-Ife, Nigeria
Certifications
- Board Certified - Pediatric Surgery
- American Board of Surgery
- Board Certified - General Surgery
- American Board of Surgery
Honors & Awards
- Master Clinician Award for Excellence in Patient Care
- Baylor College of Medicine
- 2012 Denton A. Cooley Surgical Innovator Award
- Texas Children’s Hospital
- Academy of Distinguished Educators
- Baylor College of Medicine
- Molecular Surgeon Research Achievement Award
- Michael E. DeBakey Department of Surgery
- Mark A. Wallace 2014 Catalyst Leader of the Year
- Texas Children's Hospital
Professional Interests
- Fetal surgery
- Diaphragmatic hernia
- CCAM
- Lung malformation
- Pectus excavatum, Chest wall deformities
- Omphalocele
- Gastroschisis
- Esophagus atresia
- Nissen fundoplication
Professional Statement
Dr. Oluyinka O. Olutoye has specialized clinical expertise in fetal and neonatal surgery with specific interest in congenital diaphragmatic hernia and complex wounds. Dr. Olutoye was the 2016 Co-president of the International Fetal Medicine and Surgery Society, a Fellow of the Surgical Section of the American Academy of Pediatrics and American College of Surgeons, and a Fellow of the West African College of Surgeons. He is certified by the American Board of Surgery both in general surgery and pediatric surgery. Dr. Olutoye has a broad range of research endeavors ranging from basic science research using animal models of disease to robust clinical research. He has an active basic science laboratory currently focused on three main areas of research: wound healing, necrotizing enterocolitis (NEC) and fetal interventions. Hypertrophic scarring and keloids can be disfiguring conditions for many patients. Working with a pig model for hypertrophic scars he is studying the effects of Serum Amyloid P (SAP) on fibrocyte inhibition with hopes of developing a therapy that may be translated to treatment of keloids in humans. Early diagnosis of Necrotizing Enterocolitis (NEC) continues to be a clinical challenge. Using a premature piglet model of NEC, he is attempting to identify non-invasive measure as well as serum biomarkers that will allow for early detection of neonates at risk for NEC. In collaboration with multiple subspecialty colleagues he is using time-dated pregnant sheep models to study innovative techniques in fetal intervention to treat conditions such as twin-twin transfusion syndrome (TTTS), spina bifida and congenital diaphragmatic hernia (CDH) as well as the effects of fetal anesthesia on the developing brain. Dr. Olutoye also has a great interest in the clinical application of NIRS technology for a variety of neonatal conditions: CDH patients before and after surgical correction, those undergoing extracorporeal membrane oxygenation (ECMO), neonates pre and post patent ductus arteriosus (PDA) ligation and neonates with congenital heart defects.Websites
Texas Children's Fetal Center
NBC News
TMC News
Videos
As one of the nation's leaders in the diagnosis and treatment of abnormalities in unborn and newborn infants, Texas Children’s Fetal Center™ is committed to providing the best possible care and outcome for each mother, baby and family. We provide comprehensive care to meet the needs of pregnant women, fetuses and newborns in a new model we call family-centered care.
Selected Publications
- Cassady CI, Mehollin-Ray AR, Olutoye OO, Cass DL "Jugular vein hypoplasia can preclude extracorporeal membrane oxygenation cannulation in the neonate with congenital diaphragmatic hernia: potential identification of the neonate at risk by fetal magnetic resonance imaging.." Fetal. Diagn. Ther.. 2011;30(3):225-8. Pubmed PMID: 21968417
- Gay AN, Mushin OP, Lazar DA, Naik-Mathuria BJ, Yu L, Gobin A, Smith CW, Olutoye OO "Wound healing characteristics of icam-1 null mice devoid of all isoforms of icam-1.." J. Surg. Res.. 2011 Nov;171(1):e1-7. Pubmed PMID: 21872884
- Lazar DA, Cass DL, Dishop MK, Adam K, Olutoye OA, Ayres NA, Cassady CI, Olutoye OO "Fetal lung interstitial tumor: a cause of late gestation fetal hydrops.." J. Pediatr. Surg.. 2011 Jun;46(6):1263-6. Pubmed PMID: 21683234
- Rodriguez MA, Cass DL, Lazar DA, Cassady CI, Moise KJ, Johnson A, Mushin OP, Hassan SF, Belleza-Bascon B, Olutoye OO "Tumor volume to fetal weight ratio as an early prognostic classification for fetal sacrococcygeal teratoma.." J. Pediatr. Surg.. 2011 Jun;46(6):1182-5. Pubmed PMID: 21683219
- Gay AN, Lazar DA, Stoll B, Naik-Mathuria B, Mushin OP, Rodriguez MA, Burrin DG, Olutoye OO "Near-infrared spectroscopy measurement of abdominal tissue oxygenation is a useful indicator of intestinal blood flow and necrotizing enterocolitis in premature piglets.." J. Pediatr. Surg.. 2011 Jun;46(6):1034-40. Pubmed PMID: 21683194
- Lazar DA, Olutoye OO, Cass DL, Fernandes CJ, Welty SE, Johnson KE, Rycus PT, Lee TC "Outcomes of neonates requiring extracorporeal membrane oxygenation for irreversible pulmonary dysplasia: The Extracorporeal Life Support Registry experience*.." Pediatr Crit Care Med. 2012 Mar;13(2):188-90. Pubmed PMID: 21666536
- Lazar DA, Cass DL, Rodriguez MA, Hassan SF, Cassady CI, Johnson YR, Johnson KE, Johnson A, Moise KJ, Belleza-Bascon B, Olutoye OO "Impact of prenatal evaluation and protocol-based perinatal management on congenital diaphragmatic hernia outcomes.." J. Pediatr. Surg.. 2011 May;46(5):808-13. Pubmed PMID: 21616231
- Cass DL, Olutoye OO, Cassady CI, Moise KJ, Johnson A, Papanna R, Lazar DA, Ayres NA, Belleza-Bascon B "Prenatal diagnosis and outcome of fetal lung masses.." J. Pediatr. Surg.. 2011 Feb;46(2):292-8. Pubmed PMID: 21292076
- Nadler EP, Krishnaswami S, Brundage SI, Kim LT, Kingham TP, Olutoye OO, Nwariaku F, Nwomeh BC "Assessing the efficacy of the fundamentals of research and career development course overseas.." J. Surg. Res.. 2010 Oct;163(2):197-200. Pubmed PMID: 20538295
- Santos XM, Papanna R, Johnson A, Cass DL, Olutoye OO, Moise KJ, Belleza-Bascon B, Cassady CI "The use of combined ultrasound and magnetic resonance imaging in the detection of fetal anomalies.." Prenat. Diagn.. 2010 May;30(5):402-7. Pubmed PMID: 20440730
- Raygorodskaya NY, Chernykh VB, Morozov DA, Olutoye OO, Bolotova NV, Averyanov AP, Maslyakova GN, Shilova NV, Zolotukhina TV "A 3-year-old boy with ovotestes: gender reassignment and surgical management.." J. Pediatr. Endocrinol. Metab.. 2011;24(41463):587-9. Pubmed PMID: 21932607
- Olutoye OO, Johnson MP, Coleman BG, Crombleholme TM, Adzick NS, Flake AW "Abnormal umbilical cord Dopplers may predict impending demise in fetuses with sacrococcygeal teratoma. A report of 2 cases.." Fetal. Diagn. Ther..;18(6):428-31. Pubmed PMID: 14564114
- Naik-Mathuria B, Gay AN, Zhu X, Yu L, Cass DL, Olutoye OO "Age-dependent recruitment of neutrophils by fetal endothelial cells: implications in scarless wound healing.." J. Pediatr. Surg.. 2007 Jan;42(1):166-71. Pubmed PMID: 17208559
- Thymann T, Møller HK, Stoll B, Støy AC, Buddington RK, Bering SB, Jensen BB, Olutoye OO, Siggers RH, Mølbak L, Sangild PT, Burrin DG "Carbohydrate maldigestion induces necrotizing enterocolitis in preterm pigs.." Am. J. Physiol. Gastrointest. Liver Physiol.. 2009 Dec;297(6):G1115-25. Pubmed PMID: 19808655
- Brunetti-Pierri N, Olutoye OO, Heptulla R, Tatevian N "Case report: pathological features of aberrant pancreatic development in congenital hyperinsulinism due to ABCC8 mutations.." Ann. Clin. Lab. Sci.. 2008;38(4):386-9. Pubmed PMID: 18988933
- Garcia PJ, Olutoye OO, Ivey RT, Olutoye OA "Case scenario: anesthesia for maternal-fetal surgery: the Ex Utero Intrapartum Therapy (EXIT) procedure.." Anesthesiology. 2011 Jun;114(6):1446-52. Pubmed PMID: 21555935
- Jain AK, Motil KJ, Olutoye OO, Cope-Yokoyama S, Egler RA, Tatevian N "Colon cancer in a 16-year-old girl: signet-ring cell carcinoma without microsatellite instability--an unusual suspect.." J. Pediatr. Gastroenterol. Nutr.. 2009 Jan;48(1):110-4. Pubmed PMID: 19172134
- Cass DL, Olutoye OO, Ayres NA, Moise KJ, Altman CA, Johnson A, Cassady CI, Lazar DA, Lee TC, Lantin MR "Defining hydrops and indications for open fetal surgery for fetuses with lung masses and vascular tumors.." J. Pediatr. Surg.. 2012 Jan;47(1):40-5. Pubmed PMID: 22244390
- Lazar DA, Ruano R, Cass DL, Moise KJ, Johnson A, Lee TC, Cassady CI, Olutoye OO "Defining liver-up": does the volume of liver herniation predict outcome for fetuses with isolated left-sided congenital diaphragmatic hernia?"." J. Pediatr. Surg.. 2012 Jun;47(6):1058-62. Pubmed PMID: 22703769
- Ayala JA, Naik-Mathuria B, Olutoye OO "Delayed presentation of congenital diaphragmatic hernia manifesting as combined-type acute gastric volvulus: a case report and review of the literature.." J. Pediatr. Surg.. 2008 Mar;43(3):E35-9. Pubmed PMID: 18358272
- Kibbe MR, Troppmann C, Barnett CC, Nwomeh BC, Olutoye OO, Doria C, Kim RD, Mankani MH, Corbett SA, Biffl WL, Schwarze ML "Effect of educational debt on career and quality of life among academic surgeons.." Ann. Surg.. 2009 Feb;249(2):342-8. Pubmed PMID: 19212192
- Lee TC, Olutoye OO "Evaluation of the prenatally diagnosed mass.." Semin Fetal Neonatal Med. 2012 Aug;17(4):185-91. Pubmed PMID: 22424723
- Lazar DA, Olutoye OO, Moise KJ, Ivey RT, Johnson A, Ayres N, Olutoye OA, Rodriguez MA, Cass DL "Ex-utero intrapartum treatment procedure for giant neck masses-fetal and maternal outcomes.." J. Pediatr. Surg.. 2011 May;46(5):817-22. Pubmed PMID: 21616233
- Olutoye OO, Olutoye OA "EXIT procedure for fetal neck masses.." Curr. Opin. Pediatr.. 2012 Jun;24(3):386-93. Pubmed PMID: 22498672
- Cass DL, Olutoye OO, Cassady CI, Zamora IJ, Ivey RT, Ayres NA, Olutoye OA, Lee TC "EXIT-to-resection for fetuses with large lung masses and persistent mediastinal compression near birth.." J. Pediatr. Surg.. 2013 Jan;48(1):138-44. Pubmed PMID: 23331806
- Stark RJ, Naik-Mathuria BJ, Lam FW, Olutoye OO, Sutton VR, Shekerdemian LS "Extracorporeal membrane oxygenation support of a severe metabolic crisis in a child with methylmalonic acidemia.." ASAIO J.. 2012 Jul;58(4):438-9. Pubmed PMID: 22711065
- Mehollin-Ray AR, Cassady CI, Cass DL, Olutoye OO "Fetal MR Imaging of Congenital Diaphragmatic Hernia.." Radiographics. 2012 Jul;32(4):1067-84. Pubmed PMID: 22786994
- Olutoye OO "Fetal surgery: coming to a center near you?." J Intensive Care Med.;23(1):67-9. Pubmed PMID: 18230635
- Naik-Mathuria B, Gay AN, Yu L, Hsu JE, Smith CW, Olutoye OO "Fetal wound healing using a genetically modified murine model: the contribution of P-selectin.." J. Pediatr. Surg.. 2008 Apr;43(4):675-82. Pubmed PMID: 18405715
- Naik-Mathuria B, Olutoye OO "Foregut abnormalities.." Surg. Clin. North Am.. 2006 Apr;86(2):261-84, viii. Pubmed PMID: 16580923
- Constantacos C, Lawson NM, Votanopoulos KI, Olutoye O, Eldin KW, Feigin RD "Giant thymic cyst in left lower hemithorax of a healthy teenaged athlete.." J. Thorac. Cardiovasc. Surg.. 2007 Nov;134(5):1373-4. Pubmed PMID: 17976489
- Benight NM, Stoll B, Olutoye OO, Holst JJ, Burrin DG "GLP-2 Delays But Does Not Prevent the Onset of Necrotizing Enterocolitis in Preterm Pigs.." J. Pediatr. Gastroenterol. Nutr.. 2013 Jan 21; Pubmed PMID: 23343934
- Gay AN, Chang S, Rutland L, Yu L, Byeseda S, Naik-Mathuria B, Cass DL, Russell H, Olutoye OO "Granulocyte colony stimulating factor alters the phenotype of neuroblastoma cells: implications for disease-free survival of high-risk patients.." J. Pediatr. Surg.. 2008 May;43(5):837-42. Pubmed PMID: 18485949
- Miniati D, Gay AN, Parks KV, Naik-Mathuria BJ, Hicks J, Nuchtern JG, Cass DL, Olutoye OO "Imaging accuracy and incidence of Wilms' and non-Wilms' renal tumors in children.." J. Pediatr. Surg.. 2008 Jul;43(7):1301-7. Pubmed PMID: 18639686
- Naylor MC, Lazar DA, Zamora IJ, Mushin OP, Yu L, Brissett AE, Olutoye OO "Increased in vitro differentiation of fibrocytes from keloid patients is inhibited by serum amyloid P.." Wound Repair Regen. 2012 May;20(3):277-83. Pubmed PMID: 22564223
- Fallon SC, Shekerdemian LS, Olutoye OO, Cass DL, Zamora IJ, Nguyen T, Kim ES, Larimer EL, Lee TC "Initial experience with single-vessel cannulation for venovenous extracorporeal membrane oxygenation in pediatric respiratory failure*.." Pediatr Crit Care Med. 2013 May;14(4):366-73. Pubmed PMID: 23548959
- Naik-Mathuria B, Ng G, Olutoye OO "Lytic rib lesion in a 1-year-old child: group A beta streptococcal osteomyelitis mimicking tumor.." Pediatr. Surg. Int.. 2006 Oct;22(10):837-9. Pubmed PMID: 16896820
- Zamora IJ, Ethun CG, Evans LM, Olutoye OO, Ivey RT, Haeri S, Belfort MA, Lee TC, Cass DL "Maternal morbidity and reproductive outcomes related to fetal surgery.." J. Pediatr. Surg.. 2013 May;48(5):951-5. Pubmed PMID: 23701766
- Olutoye OO, Shulman RJ, Cotton RT "Mitomycin C in the management of pediatric caustic esophageal strictures: a case report.." J. Pediatr. Surg.. 2006 May;41(5):e1-3. Pubmed PMID: 16677867
- McCord SS, Naik-Mathuria BJ, Murphy KM, McLane KM, Gay AN, Bob Basu C, Downey CR, Hollier LH, Olutoye OO "Negative pressure therapy is effective to manage a variety of wounds in infants and children.." Wound Repair Regen.;15(3):296-301. Pubmed PMID: 17537115
- Olutoye OO, Zhu X, Cass DL, Smith CW "Neutrophil recruitment by fetal porcine endothelial cells: implications in scarless fetal wound healing.." Pediatr. Res.. 2005 Dec;58(6):1290-4. Pubmed PMID: 16306210
- Suell MN, Horton TM, Dishop MK, Mahoney DH, Olutoye OO, Mueller BU "Outcomes for children with gallbladder abnormalities and sickle cell disease.." J. Pediatr.. 2004 Nov;145(5):617-21. Pubmed PMID: 15520760
- Ethun CG, Zamora IJ, Roth DR, Kale A, Cisek L, Belfort MA, Haeri S, Ruano R, Welty SE, Cassady CI, Olutoye OO, Cass DL "Outcomes of fetuses with lower urinary tract obstruction treated with vesicoamniotic shunt: A single-institution experience.." J. Pediatr. Surg.. 2013 May;48(5):956-62. Pubmed PMID: 23701767
- Edwards RM, Naik-Mathuria BJ, Gay AN, Olutoye OO, Teruya J "Parameters of thromboelastography in healthy newborns.." Am. J. Clin. Pathol.. 2008 Jul;130(1):99-102. Pubmed PMID: 18550478
- Naik-Mathuria B, Chang S, Fitch ME, Westhoff J, Brandt ML, Ayres NA, Olutoye OO, Cass DL "Patent ductus arteriosus ligation in neonates: preoperative predictors of poor postoperative outcomes.." J. Pediatr. Surg.. 2008 Jun;43(6):1100-5. Pubmed PMID: 18558190
- Alexandrescu S, Tatevian N, Olutoye O, Brown RE "Persistent hyperinsulinemic hypoglycemia of infancy: constitutive activation of the mTOR pathway with associated exocrine-islet transdifferentiation and therapeutic implications.." Int J Clin Exp Pathol. 2010;3(7):691-705. Pubmed PMID: 20830240
- Glick RD, Hicks MJ, Nuchtern JG, Wesson DE, Olutoye OO, Cass DL "Renal tumors in infants less than 6 months of age.." J. Pediatr. Surg.. 2004 Apr;39(4):522-5. Pubmed PMID: 15065020
- Miniati DN, Chintagumpala M, Langston C, Dishop MK, Olutoye OO, Nuchtern JG, Cass DL "Prenatal presentation and outcome of children with pleuropulmonary blastoma.." J. Pediatr. Surg.. 2006 Jan;41(1):66-71. Pubmed PMID: 16410110
- Naik-Mathuria B, Pilling D, Crawford JR, Gay AN, Smith CW, Gomer RH, Olutoye OO "Serum amyloid P inhibits dermal wound healing.." Wound Repair Regen.;16(2):266-73. Pubmed PMID: 18318811
- Freysdottir D, Olutoye O, Langston C, Fernandes CJ, Tatevian N "Spontaneous pulmonary interstitial emphysema in a term unventilated infant.." Pediatr. Pulmonol.. 2006 Apr;41(4):374-8. Pubmed PMID: 16447182
- Naik-Mathuria B, Okanlami OO, Olutoye OA, Tjia I, Olutoye OO "Subclavian venipuncture following ipsilateral extrapleural dissection is hazardous.." Pediatr. Surg. Int.. 2006 Jul;22(7):608-9. Pubmed PMID: 16598508
- Bauchart-Thevret C, Stoll B, Benight NM, Olutoye O, Lazar D, Burrin DG "Supplementing monosodium glutamate to partial enteral nutrition slows gastric emptying in preterm pigs.." J. Nutr.. 2013 May;143(5):563-70. Pubmed PMID: 23446960
- Lazar DA, Cass DL, Olutoye OO, Welty SE, Fernandes CJ, Rycus PT, Lee TC "The use of ECMO for persistent pulmonary hypertension of the newborn: A decade of experience.." J. Surg. Res.. 2012 Oct;177(2):263-7. Pubmed PMID: 22901797
- Lazar DA, Cassady CI, Olutoye OO, Moise KJ, Johnson A, Lee TC, Cass DL "Tracheoesophageal displacement index and predictors of airway obstruction for fetuses with neck masses.." J. Pediatr. Surg.. 2012 Jan;47(1):46-50. Pubmed PMID: 22244391
- Baharestani M, Amjad I, Bookout K, Fleck T, Gabriel A, Kaufman D, McCord SS, Moores DC, Olutoye OO, Salazar JD, Song DH, Teich S, Gupta S "V.A.C. Therapy in the management of paediatric wounds: clinical review and experience.." 2009 Aug;6:41300. Pubmed PMID: 19614789
- Lazar DA, Cass DL, Olutoye OO, Kim ES, Welty SE, Fernandes CJ, Lee TC "Venovenous cannulation for extracorporeal membrane oxygenation using a bicaval dual-lumen catheter in neonates.." J. Pediatr. Surg.. 2012 Feb;47(2):430-4. Pubmed PMID: 22325408
- Zamora IJ, Vu LT, Larimer EL, Olutoye OO "Water-absorbing balls: a growing" problem."." Pediatrics. 2012 Oct;130(4):e1011-4. Pubmed PMID: 22987870
Memberships
- American College of Surgeons
- Fellow
- American Academy of Pediatrics
- Fellow
- West African College of Surgeons
- Fellow
- Humera Surgical Society
- President, 2006
- American Pediatric Surgical Association
- Association for Academic Surgery
- Alpha Omega Alpha
- Society for University Surgeons
- Wound Healing Society
- International Fetal Medicine & Surgery Society
- Co-President 2016
- Baylor College of Medicine Faculty Senate
- Chair-elect (10/2015)
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