Email

nicholas.o'brien@bcm.edu

Positions

Medical Scientist Training Program (MD/PhD)

Baylor College of Medicine

GS1

Development, Disease Models & Therapeutics
Baylor College of Medicine

Mentor: TBD

Education

BA from Columbia University in the City of New York

05/2020 - New York, New York United States

Biochemistry

Selected Publications

• Venkatesh D, O’Brien NA, Zandkarimi F, Tong DR, Stokes ME, Dunn DE, Kengmana ES, Aron AT, Klein AM, Csuka JM, Moon SH, Conrad M, Chang CJ, Lo DC, D'Alessandro A, Prives C, Stockwell BR "MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling." Genes Dev. 2020 Apr 1;34(7-8):526-543. Pubmed PMID: 32079652
• Donahue TC, Zong G, O’Brien NA, Ou C, Gildersleeve J, Wang LX "Synthesis and Immunological Study of N-Glycan-Bacteriophage Qβ Conjugates Reveal Dominant Antibody Responses to the Conserved Chitobiose Core." Bioconjug Chem. 2022 Jul 20;33(7):1350-1362. Pubmed PMID: 35687881
• Rashidijahanabad Z, Ramadan S, O’Brien NA, Nakisa A, Lang S, Crawford H, Gildersleeve J, Huang X "Stereoselective Synthesis of Sialyl Lewisa Antigen and the Effective Anticancer Activity of Its Bacteriophage Qβ Conjugate as an Anticancer Vaccine." Angew Chem Int Ed Engl. 2023 Oct 2; Pubmed PMID: 37781858
• Tan Z†, Yang W†, O'Brien NA, Pan X, Ramadan S, Marsh T, Hammer N, Cywes-Bentley C, Vinacur M, Pier GB, Gildersleeve JC, Huang X "A comprehensive synthetic library of poly-N-acetyl glucosamines enabled vaccine against lethal challenges of Staphylococcus aureus." Nat Commun. 2024 Apr 24;15(1):3420. Pubmed PMID: 38658531