Laure Maneix, Ph.D.
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Laure Maneix, Ph.D.
Laboratory Director
Positions
- Laboratory Director
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Dan L. Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States
Addresses
- Dan L. Duncan Comprehensive Cancer Center (Office)
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Baylor College of Medicine
One Baylor Plaza, M502D
Houston, TX 77030
United States
laure.maneix@bcm.edu
Education
- PhD from University of Caen Basse-Normandie
- 04/2010 - Caen, France
- Biology, Medicine and Health with Cellular and Molecular Physiopathology speciality
- MS from University of Caen Basse-Normandie
- 06/2006 - Caen, France
- Cellular Biology, Molecular and Cellular Physiopathology
Honors & Awards
- Christa Muller-Sieburg Award
- International Society for Experimental Hematology (08/2021)
Websites
Selected Publications
- Maneix L., Sweeney M.A., Lee S., Iakova P., Moree S.E., Sahin E., Lulla P., Yellapragada S.V., Tsai F.T.F., Catic A. "The mitochondrial protease LonP1 promotes proteasome inhibitor resistance in multiple myeloma." Cancers (Basel). 2021 Feb 17;13(4):843. Pubmed PMID: 33671345
- Maneix L., Catic A. "Touch and go: nuclear proteolysis in the regulation of metabolic genes and cancer." FEBS Lett.. 2016 Apr;590(7):908-923. Pubmed PMID: 26832397
- Maneix L., Iakova P., Lee C., Moree S.E., Lu X., Datar G.K., Hill C., Spooner E., King J.C.K., Sykes D.B., Saez B., Di Stefano B., Chen X., Krause D.S., Sahin E., Tsai F.T.F., Goodell M.A., Berk B.C., Scadden D.T., Catic A. "Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing." Nat. Cell Biol.. 2024 Feb 23;26:593–603.
- Sweeney MA, Iakova P, Maneix L, Shih F-Y, Cho HE, Sahin E, Catic A "The ubiquitin ligase Cullin-1 associates with chromatin and regulates transcription of specific c-MYC target genes." Sci. Rep.. 2020 Aug 18;10(1):13942. Pubmed PMID: 32811853
- Maneix L, Antonson P, Humire P, Rochel-Maia S, Castañeda J, Omoto Y, Kim HJ, Warner M, Gustafsson JÅ "Estrogen receptor β exon 3-deleted mouse: The importance of non-ERE pathways in ERβ signaling." Proc. Natl. Acad. Sci. U.S.A. 2015 Apr 21;112(16):5135-5140. Pubmed PMID: 25848008
- Maneix L, Servent A, Porée B, Ollitrault D, Branly T, Bigot N, Boujrad N, Flouriot G, Demoor M, Boumediene K, Moslemi S, Galéra P "Up-regulation of type II collagen gene by 17β-estradiol in articular chondrocytes involves Sp1/3, Sox-9, and estrogen receptor α." J. Mol. Med. 2014 Aug 2;92(11):1179-1200. Pubmed PMID: 25081415
- Maneix L, Beauchef G, Servent A, Wegrowski Y, Maquart FX, Boujrad N, Flouriot G, Pujol JP, Boumediene K, Galéra P, Moslemi S "17Beta-oestradiol up-regulates the expression of a functional UDP-glucose dehydrogenase in articular chondrocytes: comparison with effects of cytokines and growth factors." Rheumatology (Oxford). 2008 Mar;47(3):281-288. Pubmed PMID: 18238796
Memberships
- American Association for Cancer Research (AACR)
- Member (10/2013)
- American Aging Association
- Member (01/2018)
- International Society for Experimental Hematology
- Member (04/2021)
- European Association for Cancer Research (EACR)
- Member (06/2014)
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