Katherine Ellen Pendleton
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Katherine Ellen Pendleton
Graduate Student
Positions
- Graduate Student
-
Molecular and Human Genetics
Baylor College of Medicine
Education
- BS from Georgia Institute of Technology
- 05/2018 - Atlanta, Georgia United States
- Biology: Health and Medical Sciences
Professional Statement
I am broadly interested in metabolic adaptations and the immune microenvironment in chemoresistant triple negative breast cancer (TNBC). My goal is to improve our understanding of TNBC on the genomic level and apply this knowledge into developing targeted therapeutics.Websites
Selected Publications
- "Xenomake: a pipeline for processing and sorting xenograft reads from spatial transcriptomic experiments." Bioinformatics (Accepted). 2024; Pubmed PMID: 37732227
- "Rewiring of mitochondrial metabolism in therapy-resistant cancers: permanent and plastic adaptations." Frontiers in Cell and Developmental Biology. 2023 Sep 13; Pubmed PMID: 37779896
- "FOXP1 Haploinsufficiency Contributes to the Development of Congenital Diaphragmatic Hernia." Journal of Pediatric Genetics. 2023 Mar 28; Pubmed PMID: 38567173
- "SOX7 deficiency causes ventricular septal defects through its effects on endocardial-to-mesenchymal transition and the expression of Wnt4 and Bmp2." Human Molecular Genetics. 2023 Mar 31; Pubmed PMID: 37000005
- "Mitochondrial structure and function adaptation in residual triple negative breast cancer cells surviving chemotherapy treatment." Oncogene. 2023; Pubmed PMID: 36813854
- "Aberrant extrafollicular B cells, immune dysfunction, myeloid inflammation and MyD88-mutant progenitors precede malignancy in Waldenstrom macroglobulinemia." Blood Cancer Discovery. 2021 Sep 1; Pubmed PMID: 34778800
- "Risk-associated alterations in marrow T cells in pediatric leukemia." JCI Insight. 2020 Jul 21;5(16) Pubmed PMID: 32692727
- "Early alterations in stem-like/marrow-resident T cells and innate and myeloid cells in preneoplastic gammopathy." JCI Insight. 2019 Jun 6;4(11) Pubmed PMID: 31013254
- "Differential effects of PD-L1 versus PD-1 blockade on myeloid inflammation in human cancer." JCI Insight. 2019 May 19;5(12) Pubmed PMID: 32427579
Funding
- Ruth L. Kirschstein Predoctoral Individual National Research Service Award - #F31CA275397 National Cancer Institute
- T32 Predoctoral Training Grant - #T32GM139534 National Institutes of Health
- Predoctoral Training Grant The Cullen Foundation
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