Email

James.Chang@bcm.edu

Positions

Instructor

Department of Molecular Virology and Microbiology
Maresso Group
Baylor College of Medicine

Education

BS from California Institute of Technology

06/2003 - Pasadena, CA

Chemistry

MS from University of California, San Diego

06/2011 - San Diego, CA

Chemistry

PhD from Baylor University

08/2017 - Waco, TX

Biophysical Chemistry, Microbiology

Postdoctoral Training at Baylor College of Medicine

10/2024 - Houston, TX

Microbiology

Professional Interests

• Structural biology
• Deep learning
• Protein language model
• Antimicrobial resistance and phage therapy

Selected Publications

• Xing, Y.; Clark, J.; Chang, J.; Chirman, D.; Green, S.; Zulk, J.; Jelinski, J.; Patras, K.; Maresso, A. "Broad protective vaccination against systemic Escherichia coli with autotransporter antigens." PLoS Pathog. 2023 Feb;19(2):e1011082. Pubmed PMID: 36800400
• Gu Liu, C.; Thompson, B.; Chang, J.; Min, L.; Maresso, A. "Construction and characterization of DNA libraries from cultured phages and environmental viromes." Microbiol Spectr.. 2024 Oct;90(10):e0117124. Pubmed PMID: 39315792
• Taylor, J.; Gu Liu, C.; Chang, J.; Thompson, B.; Maresso, A. "Gene discovery from microbial gene libraries I: protection against reactive oxygen species-driven DNA damage." 2024 Nov;12(11):e0036524. Pubmed PMID: 39283089
• Chang, J.; Vaughan, E.; Gu Liu, C.; Jelinski, J.; Terwilliger, A.; Maresso, A. "Metabolic profiling reveals nutrient preferences during carbon utilization in Bacillus species." Sci Rep.. 2021 Dec;11(1):23917. Pubmed PMID: 34903830