Erin Christine Peckham-Gregory, Ph.D., M.P.H.
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Positions
- Assistant Professor
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Pediatrics
Hematology-Oncology
Baylor College of Medicine
Houston, TX US
Education
- Postdoctoral Fellowship at Baylor College of Medicine
- 06/2017 - Houston, Texas United States
- NCI-funded R25T fellowship program in Pediatric Cancer Epidemiology and Control
- PhD from University of California at Los Angeles
- 09/2014 - Los Angeles, California United States
- Cancer Epidemiology
- MPH from University of California at Los Angeles
- 06/2009 - Los Angeles, California United States
- Epidemiology
- BS from University of California at Los Angeles
- 06/2007 - Los Angeles, California United States
- Ecology and Evolutionary Biology
Professional Statement
Research Focus: I am a molecular epidemiologist whose primary research focus is to elucidate inherited genetic effects and epidemiologic factors underlying susceptibility to pediatric lymphoproliferative and HIV-related malignancies. I have developed local, national and global collaborations with experts in the fields of Langerhans cell histiocytosis (LCH) and lymphoma to assess epidemiologic and genetic predictors of these pediatric cancers. The resulting studies are designed to better understand the molecular underpinnings of these malignancies through an integrated approach. To assess the multifactorial aspects of pediatric HIV-related malignancies, I have ongoing collaborations with members of the Global Hematology-Oncology Pediatric Excellence Program and Baylor International Pediatric AIDS Initiative at Texas Children’s Hospital. A secondary focus is to evaluate racial/ethnic disparities and the impact of genomic ancestry on susceptibility to pediatric cancer and subsequent adverse events.Websites
Selected Publications
- Peckham-Gregory EC, Chakraborty R, Scheurer ME, Belmont JW, Abhyankar H, Sengal AG, Scull BP, Eckstein OE, Zinn DJ, Mayer L, Shih A, Merad M, Parsons DW, McClain KL, Lupo PJ, Allen CE "A genome-wide association study of LCH identifies a variant in SMAD6 associated with susceptibility." Blood. 2017;130(20):2229-2232. Pubmed PMID: 28935696
- Peckham-Gregory EC, McClain KL, Allen CE, Scheurer ME, Lupo PJ "The role of parental and perinatal characteristics on Langerhans cell histiocytosis: characterizing increased risk among Hispanics." Ann Epidemiol. 2018;28(8):521-528. Pubmed PMID: 29724524
- Eckstein OS, Visser J, Rodriguez-Galindo C, Allen CE; NACHO-LIBRE Study Group: Zinn DJ, Peckham-Gregory EC, Lin H, Henry MM, Morland B, Fein Levy C, Kumar A, Schiff D, Karras N, Chu RL, Abla O, Hijiya N, Kim SY, Campbell PK, Woods-Swafford, et. al. "Clinical responses and persistent BRAF V600E+ blood cells in children with LCH treated with MAPK pathway inhibition." Blood. 2019;133(15):1691-1694. Pubmed PMID: 30718231
- Chinn IK, Eckstein OS, Peckham-Gregory EC, Goldberg BR, Forbes LR, Nicholas SK, Mace EM, Vogel TP, Abhyankar HA, Diaz MI, Heslop HE, Krance RA, Martinez CA, Nguyen TC, Bashir DA, Goldman JR, Stray-Pedersen A, Pedroza LA, Poli MC, et. al "Genetic and mechanistic diversity in pediatric hemophagocytic lymphohistiocytosis." Blood. 2018;132(1):89-100. Pubmed PMID: 29632024
- Kamiyango W, Villiera J, Silverstein A, Peckham-Gregory E, Campbell LR, El-Mallawany NK "Navigating the heterogeneous landscape of pediatric Kaposi sarcoma." Cancer and Metastasis Reviews. 2019;38(4):749-758. Pubmed PMID: 31845111
- El-Mallawany NK, Kamiyango W, Villiera J, Peckham-Gregory EC, Scheurer ME, McAtee CL, Allen CE, Kovarik CL, Frank D, Eason AB, Caro-Vegas C, Chiao EY, Schutze GE, Ozuah NW, Mehta PS, Kazembe PN, Dittmer DP "Kaposi Sarcoma Herpesvirus Inflammatory Cytokine Syndrome (KICS)-like Clinical Presentation in HIV-Infected Children in Malawi." Clinical Infectious Diseases. 2019;69(11):2022-2025. Pubmed PMID: 31102440
- El-Mallawany NK, Mehta PS, Kamiyango W, Villiera J, Peckham-Gregory EC, Kampani C, Krysiak R, Sanders MK, Caro-Vegas C, Eason AB, Ahmed S, Schutze GE, Martin SC, Kazembe PN, Scheurer ME, Dittmer DP "KSHV Viral Load and Interleukin-6 in HIVAssociated Pediatric Kaposi Sarcoma—Exploring the Role of Lytic Activation in Driving the 5 Unique Clinical Features Seen in Endemic Regions." International Journal of Cancer. 2019;144(1):110-116. Pubmed PMID: 30204240
- El-Mallawany NK, Villiera J, Kamiyango W, Peckham-Gregory EC, Scheurer ME, Allen CE, McAtee CL, Legarreta A, Dittmer DP, Kovarik CL, Chiao EY, Martin SC, Ozuah NW, Mehta PS, Kazembe PN "Endemic Kaposi Sarcoma in HIV-Negative Children and Adolescents: An Evaluation of Overlapping and Distinct Clinical Features in Comparison with HIV-Related Disease." Infectious Agents and Cancer. 2018;13(33) Pubmed PMID: 30455728
- Peckham-Gregory EC, Thapa DR, Martinson J, Duggal P, Penugonda S, Bream JH, Chang P, Dandekar U, Chang SC, Detels R, Martínez-Maza O, Zhang ZF, Hussain SK "MicroRNA-related polymorphisms and non-Hodgkin lymphoma susceptibility in the Multicenter AIDS cohort stud." Cancer Epidemiology. 2016;45:47-57. Pubmed PMID: 27701053
- Peckham-Gregory EC, Danysh HE, Brown A, Eckstein O, Grimes A, Chakraborty R, Lubega J, McClain KL, Allen CE, Scheurer ME, Lupo PJ "Evaluation of Maternal and Perinatal Characteristics on Childhood Lymphoma Risk: A Population-Based Case-Control Study." Pediatric Blood and Cancer. 2016;64(5) Pubmed PMID: 27896915
- Peckham EC, Scheurer ME, Danysh HE, Lubega J, Langlois PH, Lupo PJ "Residential Radon Exposure and Incidence of Childhood Lymphoma in Texas, 1995–2011." International Journal of Environmental Research and Public Health. 2015;12(10):12110-12126. Pubmed PMID: 26404336
- Peckham-Gregory EC, Ton M, Rabin KR, Danysh HE, Scheurer ME, Lupo PJ "Maternal Residential Proximity to Major Roadways and the Risk of Childhood Acute Leukemia: A Population-Based Case-Control Study in Texas, 1995-2011." International Journal of Environmental Research and Public Health. 2019;16(11):E2029. Pubmed PMID: 31181608
- Archer NP, Perez-Andreu V, Stoltze U, Scheurer ME, Wilkinson AV, Goodings C, Swartz MD, Ranjit N, Rabin KR, Peckham-Gregory EC, Plon SE, de Alarcon PA, Zabriskie RC, Antillon-Klussmann F, Najera CR, Yang JJ, Lupo PJ "Family-based exome-wide association study of childhood acute lymphoblastic leukemia among Hispanics confirms role of ARID5B in susceptibility." Plos One. 2017;12(8):e0180488. Pubmed PMID: 28817678
- Archer NP, Perez-Andreu V, Scheurer ME, Rabin KR, Peckham-Gregory EC, Plon SE, Zabriskie RC, De Alarcon PA, Fernandez KS, Najera CR, Yang JJ, Antillon-Klussmann F, and Lupo PJ "Family-based exome-wide assessment of maternal genetic effects on susceptibility to childhood B-cell acute lymphoblastic leukemia in hispanics." Cancer. 2016;122(23):3697-3704. Pubmed PMID: 27529658
- Schraw J, Peckham-Gregory EC, Rabin K, Scheurer ME, Lupo PJ, Oluyomi A "Area Deprivation is Associated with Poorer Overall Survival in Children with Acute Lymphoblastic Leukemia." Pediatric Blood and Cancer. 2020;Jun 23:e28525.
Memberships
- Children's Oncology Group
- Hodgkin Lymphoma Committee Member (09/2018)
- International Society of Pediatric Oncology
- Young Investigator Network Board Member (11/2019)
- International Lymphoma Epidemiology Consortium
- Member (06/2014)
- American Society of Hematology
- Member (11/2017)
- Histiocyte Society
- Member (09/2016)
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