Dah-eun Chloe Chung, Ph.D.
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Dah-eun Chloe Chung, Ph.D.
Postdoctoral Associate
Positions
- Postdoctoral Associate
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Department of Molecular & Human Genetics
Laboratory of Dr. Huda Zoghbi
Baylor College of Medicine
Houston, TX US
Education
- BA from Washington University in St. Louis
- 05/2012 - St. Louis, Missouri United States
- Biochemistry
- PhD from Mayo Clinic Graduate School of Biomedical Sciences
- 05/2019 - Jacksonville, Florida United States
- Neuroscience
Professional Interests
- Neurodegenerative diseases
Selected Publications
- Chung DC, Deng X, Yalamanchili H, Revelli JP, Han A, Tadros B, Richman R, Dias M, Naini FA, Boeynaems S, Hyman BT, and Zoghbi HY "The big tau splice isoform resists Alzheimer’s-related pathological changes." bioRxiv. 2024 Jul 31; Pubmed PMID: 39211086
- Chung DC, Roemer S, Petrucelli L, and Dickson DW "Cellular and pathological heterogeneity of primary tauopathies." Mol Neurodegener. 2021 Aug 23;16(1):57. Pubmed PMID: 34425874
- Chung DC, Carlomagno Y, Cook CN, Jansen-West K, Daughrity L, Lewis-Tuffin LJ, Castanedes-Casey M, DeTure M, Dickson DW, Petrucelli L "Tau exhibits unique seeding properties in globular glial tauopathy." Acta Neuropathol Commun. 2019 Mar 7;7(1):36. Pubmed PMID: 30845985
- Carlomagno Y, Chung DC, Yue M, Kurti A, Avendano NM, Castanedes-Casey M, Hinkle KM, Jansen-West K, Daughrity LM, Tong J, Phillips V, Rademakers R, DeTure M, Fryer JD, Dickson DW, Petrucelli L, Cook C "Enhanced phosphorylation of T153 in soluble tau is a defining biochemical feature of the A152T tau risk variant." Acta Neuropathol Commun. 2019 Jan 23;7(1):10. Pubmed PMID: 30674342
- Carlomagno Y, Chung DC, Yue M, Castanedes-Casey M, Madden BJ, Dunmore J, Tong J, DeTure M, Dickson DW, Petrucelli L, Cook C "An acetylation-phosphorylation switch that regulates tau aggregation propensity and function." J Biol Chem. 2017 Sep 15;292(37):15277-15286. Pubmed PMID: 28760828
- Kim J, Yoon H, Chung DE, Brown JL, Belmonte KC, Kim J "miR-186 is decreased in aged brain and suppresses BACE1 expression." J Neurochem. 2016 May;137(3):436-45. Pubmed PMID: 26710318
- Kim J, Tadros B, Liang YH, Kim Y, Lasagna-Reeves C, Sonn JY, Chung DC, Hyman B, Holtzman DM, Zoghbi HY "TYK2 regulates tau levels, phosphorylation, and aggregation in tauopathy model mice." Nat Neuro. 2024;
Projects
- Investigation of the big tau splice isoform
- Identification of novel tau regulators
Funding
- Alzheimer's Disease Research Postdoctoral Fellowship BrightFocus Foundation
- CAND Scholar Center for Alzheimer’s and Neurodegenerative Diseases
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