Positions
- Lead, Clinical Research
-
Psychiatry & Behavioral Sciences - Neuropsychiatry
Baylor College of Medicine
Houston, US
Addresses
- Office (Office)
-
1 Baylor Plaza S104N
Houston, TX 77030
United States
Phone: (832) 271-6615
chris.averill@bcm.edu
Education
- BS from Westminster College
- 06/2005 - Salt Lake City, Utah United States
- Biology
Websites
Videos
This video was created in Blender using meshes from one of the combat control (non-PTSD) participants described in the manuscript. It demonstrates the gray matter subfields of the hippocampal formation, and steps through the anatomy to better visualize the more hidden subfields.
See:
Averill, C.L., Satodiya, R.M., Scott, J.C., Wrocklage, K.M., Schweinsburg, B., Averill, L.A., Akiki, T.J., Amoroso, T., Southwick, S.M., Krystal, J.H., Abdallah, C.G. (2017). PTSD and depression symptom severities are differentially associated with hippocampal subfield volume loss in combat veterans. Chronic Stress, 1.
Selected Publications
- Averill CL, Abdalla CG, Averill LA "When the "Golden Chain" Breaks: Sleep Disturbance and the Vicious Cycle of Chronic Stress." Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 Dec;4(12):1018-1020. Pubmed PMID: 31812223
- Averill CL, Averill LA, Wreckage KM, Scott JC, Akiki TJ, Schweinsburg B, Southwick SM, Krystal JH, Abdallah CG "Altered White Matter Diffusivity of the Cingulum Angular Bundle in Posttraumatic Stress Disorder." Mol Neuropsychiatry. 2018 Oct;4(2):75-82. Pubmed PMID: 30397595
- Averill CL, Averill LA, Fan S, Abdallah CG "Of Forests and Trees: Bridging the Gap Between Neurobiology and Behavior in Posttraumatic Stress Disorder." Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Feb;5(2):35-137. Pubmed PMID: 32035611
- Averill CL, Satodiya RM, Scott JC, Wrocklage KM, Schweinsburg B, Averill LA, Akiki TJ, Amoroso T, Southwick SM, Krystal JH, Abdallah CG "Posttraumatic Stress Disorder and Depression Symptom Severities Are Differentially Associated With Hippocampal Subfield Volume Loss in Combat Veterans." Chronic Stress. 2017; Pubmed PMID: 29520395
- Averill LA, Averill CL, Gueorguieva R, Fouda S, Sherif M, Ahn KH, Ranganathan M, D'Souza DC, Southwick SM, Sanacora G, Duman RS, Krystal JH, Abdallah CG "mTORC1 inhibitor effects on rapid ketamine-induced reductions in suicidal ideation in patients with treatment-resistant depression." J Affect Disord. 2022;(303):91-97. Pubmed PMID: 35101523
- Averill LA, Jiang L, Purohit P, Coppoli A, Averill CL, Roscoe J, Kelmendi B, De Feyter HM, de Graaf RA, Gueorguieva R, Sanacora G, Krystal JH, Rothman DL, Mason GF, Abdallah CG "Prefrontal Glutamate Neurotransmission in PTSD: A Novel Approach to Estimate Synaptic Strength in Vivo in Humans." Chronic Stress. 2022;24705470221092734. Pubmed PMID: 35434443
- Ragnhildstveit A, Roscoe J, Bass LC, Averill CL, Abdallah CG, Averill LA "The potential of ketamine for posttraumatic stress disorder: a review of clinical evidence." Ther Adv Psychopharmacol. 2023 Mar; Pubmed PMID: 36895431
- Clausen AN, Fercho KA, Monsour M, Disner S, Salminen L, Haswell CC, Rubright EC, Watts AA, Buckley MN, Maron-Katz A, Sierk A, Manthey A, Suarez-Jimenez B, Olatunji BO, Averill CL [and other authors for the ENIGMA PTSD and brain age working groups] "Assessment of brain age in posttraumatic stress disorder: Findings from the ENIGMA PTSD and brain age working groups." Brain Behav. 2022;12(2) Pubmed PMID: 34907666
- Adams TG, Cisler JM, Kelmendi B, George JR, Kichuk SA, Averill CL, Anticevic A, Abdallah CG, Pittenger C "Transcranial direct current stimulation targeting the medial prefrontal cortex modulates functional connectivity and enhances safety learning in obsessive-compulsive disorder: Results from two pilot studies." Depress Anxiety. 2022 Jan;39(1):37-48. Pubmed PMID: 34464485
- Zhu X, Kim Y, Ravid O, He X, Suarez-Jimenez B, Zilcha-Mano S, Lazarov A, Lee S, Abdallah CG, Angstadt M, Averill CL, [and other authors from the ENIGMA-PGC PTSD consortium] "Neuroimaging-based classification of PTSD using data-driven computational approaches: A multisite big data study from the ENIGMA-PGC PTSD consortium." NeuroImage. 2023 Dec;283 Pubmed PMID: 37858907
- Tamman AJF, Jiang L, Averill CL, Mason GF, Averill LA, Abdallah CG "Biological embedding of early trauma: the role of higher prefrontal synaptic strength." Eur J Psychotraumatol. 2023;14(2) Pubmed PMID: 37642398
- Averill LA, Averill CL, Akiki TJ, Abdallah CG "Chapter 9: Examining Neurocircuitry and neuroplasticity in PTSD. In: Friedman MJ, Schnurr PP, and Keane TM, eds. Handbook of PTSD, Science and Practice. 3rd ed. Guilford Press.." 2021;152-167.
- Yip SW, Lichenstein SD, Garrison K, Averill CL, Viswanath H, Salas R, Abdallah CG "Effects of Smoking Status and State on Intrinsic Connectivity." Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 Sep;7(9) Pubmed PMID: 33618016
- Fan S, Nemati S, Akiki TJ, Roscoe J, Averill CL, Fouda S, Averill LA, Abdallah CG "Pretreatment brain connectome fingerprint predicts treatment response in major depressive disorder." Chronic Stress. 2020;4 Pubmed PMID: 33458556
- Dai D, Lacadie CM, Holmes SE, Cool R, Anticevic A, Averill CL, Abdallah CG, Esterlis I "Ketamine normalizes the structural alterations of inferior frontal gyrus in depression." Chronic Stress. 2020;4 Pubmed PMID: 33426409
- Abdallah CG, Ahn K, Averill LA, Nemati S, Averill CL, Fouda S, Ranganathan M, Morgan PT, D'Souza DC, Mathalon DH, Krystal JH, Driesen NR "A robust and reproducible connectome fingerprint of ketamine is highly associated with the connectomic signature of antidepressants." Neuropsychopharmacology. 2021;46(2) Pubmed PMID: 32967000
- Averill LA, Averill CL, Abdallah CG "Neurobiological mechanisms of ketamine: Depression, suicide, trauma and other chronic stress pathologies." Psychiatr Ann. 2020;50(2)
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