Email

chiou-tsun.tsai@bcm.edu

Positions

Instructor

Center for Cell and Gene Therapy
Molecular and Cellular Biology
Baylor College of Medicine
Houston, US

Education

PhD from King's College London

London, United Kingdom

Cancer Studies

MSc from National Taiwan University

TAIPEI, TAIWAN, Taiwan

Microbiology and Immunology

Professional Interests

• Novel synthetic receptor design for improving T-cell functionality in cancer therapy
• Genetic engineering and development of immune cell lines for adative cell therapy

Selected Publications

• Chiou-Tsun Tsai, Jorge Andres Ibanez, Norihiro Watanabe, Giedre Krenciute, Maksim Mamonkin "An Immune Synapse-Stabilizing Receptor Enhances Sensitivity of CAR-and TCR-Mediated Tumor Targeting." Molecular Therapy. 2024 Apr 22;32:49-50.
• Feiyan Mo, Chiou-Tsun Tsai, Rong Zheng, Chonghui Cheng, Helen E Heslop, Malcolm K Brenner, Maksim Mamonkin, Norihiro Watanabe "Human platelet lysate enhances in vivo activity of CAR-Vδ2 T cells by reducing cellular senescence and apoptosis." Cytotherapy. 2024 Aug;26:858. Pubmed PMID: 38506769
• Bernd B Zeisig, Tsz Kan Fung, Magdalena Zarowiecki, Chiou Tsun Tsai, Huacheng Luo, Boban Stanojevic, Claire Lynn, Anskar YH Leung, Jan Zuna, Marketa Zaliova, Martin Bornhauser, Malte von Bonin, Boris Lenhard, Suming Huang, Ghulam J Mufti, Chi Wai Eric So "Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia." Sci Transl Med .. 2021 Feb;13:eabc482. Pubmed PMID: 33627486
• Chiou-Tsun Tsai, Chi Wai Eric So "Epigenetic therapies by targeting aberrant histone methylome in AML: molecular mechanisms, current preclinical and clinical development." Oncogene.;13:1753. Pubmed PMID: 27593928