Balasubramanium Vijayalakshmi Ayyar, Ph.D.
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Positions
- Senior Staff Scientist
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Virol & Micro
Baylor College of Medicine
Houston, Texas United States
Addresses
- BCM-Jewish Institute for Research (Lab)
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Room: 903D
Houston, TX 77030
United States
Education
- BSc from Govt. Motilal Vigyan Mahavidyalaya (MVM)
- Bhopal, Madhya Pradesh India
- MSc from Barkatullah University
- Bhopal, Madhya Pradesh India
- Fellowship at High Security Animal Disease Laboratory
- Bhopal, Madhya Pradesh India
- PhD from Dublin City University
- Dublin, Dublin Ireland
- Post-Doctoral Fellowship at Biomedical Diagnostics Institute (BDI), Dublin City University
- Dublin, Dublin Ireland
Selected Publications
- Stephen Hearty, Paul J Conroy, B Vijayalakshmi Ayyar, Barry Byrne, Richard O’Kennedy "Surface plasmon resonance for vaccine design and efficacy studies: recent applications and future trends." Expert Rev Vaccines. 2010 Jun;9(6):645-664. Pubmed PMID: 20518719
- B Vijayalakshmi Ayyar, Stephen Hearty, Richard O’Kennedy "Highly sensitive recombinant antibodies capable of reliably differentiating heart-type fatty acid binding protein from noncardiac isoforms." Anal Biochem. 2010 Dec;15(2):165-171. Pubmed PMID: 20696127
- B Vijayalakshmi Ayyar, Sushrut Arora, Caroline Murphy, Richard O’Kennedy "Affinity chromatography as a tool for antibody purification." Methods. 2012 Feb;56(2):116-129. Pubmed PMID: 22033471
- B Vijayalakshmi Ayyar, Stephen Hearty, Richard O’Kennedy "Facile domain rearrangement abrogates expression recalcitrance in a rabbit scFv.." Appl Microbiol Biotechnol. 2015;99(6):2693-2703. Pubmed PMID: 25535092
- B. Vijayalakshmi Ayyar, K. Roger Aoki and M. Zouhair Atassi "The C-Terminal Heavy-Chain Domain of Botulinum Neurotoxin A Is Not the Only Site That Binds Neurons, as the N-Terminal Heavy-Chain Domain Also Plays a Very Active Role in Toxin-Cell Binding and Interactions." Infect Immun.. 2015 Apr;83(4):1465-1476. Pubmed PMID: 25624352
- Sushrut Arora, B. Vijayalakshmi Ayyar, Richard O’Kennedy "Affinity chromatography for antibody purification.." Methods Mol Biol.. 2014;1129:497-516. Pubmed PMID: 24648096
- B. Vijayalakshmi Ayyar, Rajeev B. Tajhya, Christine Beeton and M. Zouhair Atassi "Antigenic sites on the HN domain of botulinum neurotoxin A stimulate protective antibody responses against active toxin." Sci Rep. 2015 Oct 28;5:15776. Pubmed PMID: 26508475
- B. Vijayalakshmi Ayyar and M. Zouhair Atassi "Effects of membrane properties on the binding activities of the H N and H C heavy-chain domains of botulinum neurotoxin A." Biochim Biophys Acta. 2016 Dec;1864(12):1678-1685. Pubmed PMID: 27596061
- B Vijayalakshmi Ayyar, Sushrut Arora, Richard O’Kennedy "Coming-of-Age of Antibodies in Cancer Therapeutics." Trends Pharmacol Sci. 2016;37(12):1009-1028. Pubmed PMID: 27745709
- Sushrut Arora, Vikas Saxena, B. Vijayalakshmi Ayyar "Affinity chromatography: A versatile technique for antibody purification.." Methods. 2017;116:84-94. Pubmed PMID: 28012937
- B Vijayalakshmi Ayyar, Sushrut Arora, Shiva Shankar Ravi "Optimizing antibody expression: The nuts and bolts.." Methods. 2017;116:51-62. Pubmed PMID: 28163103
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