Email

angelina.bortoletto@bcm.edu

Positions

Medical Scientist Training Program (MD/PhD)

Baylor College of Medicine
Houston, TX US

MS4

Translational Biology and Molecular Medicine
Baylor College of Medicine
Houston, Texas United States
Mentor - Ronald Parchem, PhD

Education

BS from New Mexico State University

05/2012 - Las Cruces, NM

Biochemistry

PhD from Baylor College of Medicine

08/2023 - Houston, Texas

Professional Interests

• Department: Translational Biology & Molecular Medicine
• Mentor: Ron Parchem, Ph.D
• Pathology

Selected Publications

• Bortoletto AS, Parchem RJ "A pancreatic player in dementia: pathological role for islet amyloid polypeptide accumulation in the brain.." Neural Regen Res.. 2023 Oct;18(10):2141-2146. Pubmed PMID: 37056121
• Sylvester CB, Amirkhosravi F, Bortoletto AS, West WJ 3rd, Connell JP, Grande-Allen KJ "Dantrolene inhibits lysophosphatidylcholine-induced valve interstitial cell calcific nodule formation via blockade of the ryanodine receptor." Front Cardiovasc Med. 2023 Mar 30;10 Pubmed PMID: 37063962
• Bortoletto AS, Graham WV, Trout G, Bonito-Oliva A, Kazmi MA, Gong J, Weyburne E, Houser BL, Sakmar TP, Parchem RJ "Human Islet Amyloid Polypeptide (hIAPP) Protofibril-Specific Antibodies for Detection and Treatment of Type 2 Diabetes." Adv. Sci.. 2022 Oct 18;9(34):e2202342. Pubmed PMID: 36257905
• Bortoletto AS, Parchem RJ "KRAS Hijacks the miRNA Regulatory Pathway in Cancer." Cancer Res.. 2023 May 15;83(10):1563-1572. Pubmed PMID: 36946612