Abigail Moye, PH.D.
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Abigail Moye, PH.D.
Postdoctoral Fellow
Positions
- Postdoctoral Fellow
-
Biochemistry-Wensel Lab
Baylor College of Medicine
Houston, TX US
Addresses
- BCM-Alkek Graduate School (Lab)
-
Room: BCMN-N430
Houston, TX 77030
United States
Education
- BS from Marshall University
- 05/2013 - Huntington, West Virginia United States
- PhD from West Virginia University
- 11/2018 - Morgantown, West Virginia United States
Honors & Awards
- Deans Award of Excellence
- Baylor College of Medicine
- 1st Place Members-In-Training Poster Award
- ARVO International Conference
- Postdoctoral Association President
- Baylor College of Medicine (02/2021 - 07/2022)
Professional Development
- ARL2BP, a ciliopathy protein linked to retinitis pigmentosa, controls axonemal growth
- Conference (Presenter, 2017)
- Sponsor: FASEB Biology of Cilia and Flagella
- Invited Speaker
- ARL2BP, a ciliopathy protein linked to retinitis pigmentosa, controls axonemal growth
- Conference (Presenter, 2017)
- Sponsor: ARVO
- ARL2BP, a ciliopathy protein linked to retinitis pigmentosa, controls axonemal growth
- Conference (Presenter, 2017)
- Sponsor: Annual Van Liere Convocation Research Award, West Virginia University
- 1st Place
- ARL2BP in health and disease
- Conference (Presenter, 2016)
- Sponsor: ARVO
- Invited Speaker
Selected Publications
- Tanya L Dilan 1 2, Abigail R Moye 1 2, Ezequiel M Salido 1, Thamaraiselvi Saravanan 1, Saravanan Kolandaivelu 1 2, Andrew F X Goldberg 3, Visvanathan Ramamurthy 4 2 5 "ARL13B, a Joubert Syndrome-Associated Protein, Is Critical for Retinogenesis and Elaboration of Mouse Photoreceptor Outer Segments." J Neurosci .. 2019 Feb;20(39):1347-1364. Pubmed PMID: 30573647
- Abigail R Moye 1 2, Ratnesh Singh 2, Victoria A Kimler 3, Tanya L Dilan 1 2, Daniella Munezero 1 2, Thamaraiselvi Saravanan 1, Andrew F X Goldberg 3, Visvanathan Ramamurthy 1 2 4 "ARL2BP, a protein linked to retinitis pigmentosa, is needed for normal photoreceptor cilia doublets and outer segment structure." Mol Biol Cell. 2018 Jul 1;29(13):1590-1598. Pubmed PMID: 29718757
- Tanya L Dilan 1 2, Ratnesh K Singh 1 2, Thamaraiselvi Saravanan 1, Abigail Moye 1 2, Andrew F X Goldberg 3, Peter Stoilov 2, Visvanathan Ramamurthy 1 2 4 "Bardet-Biedl syndrome-8 (BBS8) protein is crucial for the development of outer segments in photoreceptor neurons." Hum Mol Genet. 2018 Jan 15;27(2):283-294. Pubmed PMID: 29126234
- Darius J Devlin 1 2, Smriti Agrawal Zaneveld 3 4, Kaori Nozawa 2 5, Xiao Han 3 4 6, Abigail R Moye 7, Qingnan Liang 3 4 7, Jacob Michael Harnish 4, Martin M Matzuk 2 4 5, Rui Chen 3 4 "Knockout of mouse receptor accessory protein 6 leads to sperm function and morphology defects." Biol Reprod. 2020 May 26;102(6):1234-1247. Pubmed PMID: 32101290
- Abigail R Moye, Nicola Bedoni, et. al. "Mutations in ARL2BP, a protein required for ciliary microtubule structure, cause syndromic male infertility in humans and mice." PLoS Genet.. 2019 Aug 19;15(8):e1008315. Pubmed PMID: 31425546
- Valencia L Potter 1 2 3, Abigail R Moye 1, Michael A Robichaux 1 4, Theodore G Wensel 1 "Super-resolution microscopy reveals photoreceptor-specific subciliary location and function of ciliopathy-associated protein CEP290." JCI Insight .. 2021 Oct 22;6(20):e145256. Pubmed PMID: 34520396
Funding
- Cep290 function in photoreceptor structure and disease. - #EY031574 (08/10/2021 - 08/12/2024) Grant funding from NIH F32
- Ciliopathies are a group of diseases caused by defects in the cilia and lead to syndromic diseases affecting multiple organs, including the eye. This proposal will investigate the role for a ciliopathy protein that is associated with multiple ciliopathies and blindness in humans. The completion of the proposed work is important for the identification of novel therapeutic approaches and will lay the foundation for the successful completion of clinical trials that will help patients around the world.
Skills
- STORM microscopy
- TEM
- SIM Microscopy
- Cloning
- Mouse line generation/CRISPR
- Molecular Biology
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