Department of Pediatrics

Infectious Diseases Research

Master
Content

Research on infectious diseases within emergency medicine plays a crucial role in understanding and effectively managing the spread and impact of infectious agents in acute care settings. This research focuses on various aspects, including surveillance and early detection of emerging pathogens, evaluating diagnostic techniques, studying the efficacy of antimicrobial treatments, and developing strategies to prevent healthcare-associated infections. By investigating the epidemiology, transmission dynamics, and clinical manifestations of infectious diseases in emergency departments, researchers aim to enhance the diagnosis, treatment, and prevention of these conditions, ultimately improving patient outcomes and public health preparedness.

Our research chief, Andrea Cruz, is dual-boarded in PEM and ID, and is the current chair of the Pediatric Emergency Medicine Collaborative Research Committee (PEM CRC), where she led a 23-center study of neonatal herpes simplex virus and has been the site PI on other multicenter studies on hemolytic uremic syndrome, fusobacterial infections, omphalitis, and mastitis. She is a consultant to the Centers for Disease Control and Prevention and the World Health Organization (WHO) for childhood tuberculosis. She participated in the updated Surviving Sepsis pediatric guidelines.

Shubhada Hooli has worked extensively on the prevention of morbidity and mortality for young children with pneumonia in low- and middle-income countries (LMICs). She has served as a WHO consultant for childhood pneumonia and is a member of the WHO's Research Partnership to Assess WHO Recommendations (WHO PREPARE) and the Pediatric Acute Lung Injury and Sepsis Investigators Global Health (PALISI-GH) network. Nina Singh, a recipient of the Section on Emergency Medicine's Ken Graff Emerging Investigator Award, is the PECARN site PI for a study evaluating fluid resuscitation for children STEC organisms to prevent progression to hemolytic uremic syndrome. She was also the PI of a prospective interventional study on treatment modalities for oral ulcers.

Faculty with a research focus on infectious diseases:

Chokkalla AK, Tam E, Liang R, Cruz AT, Devaraj S. Validation of a multi-analyte immunoassay for distinguishing bacterial vs. viral infections in a pediatric cohortClin Chim Acta. 2023. PMID 37201742.

Lubell TR, Cruz AT, Tanverdi MS, Ochs JB, Lobritto S, Saini S, Mavrogiorgos E, Dayan PS. Bacteremia in pediatric liver transplant recipientsPediatr Infect Dis J. 2023. PMID 37171971.

Cruz AT, Seddon JA. Vulnerable children with presumptive tuberculosis: when will this population be prioritized? Pediatrics. 2023. PMID 36950927.

Chiang SS, Waterous PM, Atieno VF, Bernays S, Bondarenko Y, Cruz AT, et al. Caring for adolescents and young adults with tuberculosis or at risk of tuberculosis: consensus statement from an international expert panelJ Adolesc Health. 2023. PMID 36803849.

Hooli S, King C, McCollum ED, Colubourn T, Lufesi N, Mwansambo C, Gregory CJ, Thamthitiwat S, Cutland C, Madhi SA, Nunes MC, Gessner BD, Hazir T, Mathew JL, Addo-Yobo E, Chisaka N, Hassan M, Hibberd PL, Jeena P, Lozano JM, MacLeod WB, Patel A, Thea DM, Nguyen NTV, Zaman SM, Ruvinsky RO, Lucero M, Kartasasmita CB, Turner C, Asghar R, Banajej S, Iqbal I, Maluen-Radovan I, Mino-Leon G, Saha SK, Santosham M, Singhi S, Awasthi S, Bavdekar A, Chou M, Nymadawa P, Pape JW, Paranhos-Baccala G, Picot VS, Rakoto-Andrianarivelo M, Rouzier V, Russomando G, Sylla M, Vanhems P, Wang J, Basnet S, Strand TA, Neuman MI, Arroyo LM, Echavarria M, Bhatnagar S, Wadhwa N, Lodha R, Aneja S, Gentile A, Chadha M, Hirve S, O'Grady KF, Clara AW, Rees CA, Campbell H, Nair H, Falconer J, Williams LJ, Horne M, Qazi SA, Nisar YB; Pneumonia REsearch Partnership to Assess WHO REcommendations (PREPARE) study group. In-hospital mortality risk stratification in children aged under 5 years with pneumonia with or without pulse oximetry: A secondary analysis of the Pneumonia REsearch Partnership to Assess WHO REcommendations (PREPARE) datasetInt J Infect Dis. 2023. PMID 36805325.

Martin H, Falconer J, Addo-Yobo E, Aneja S, Arroyo LM, Asghar R, Awasthi S, Banajeh S, Bari A, Basnet S, Bavdekar A, Bhandari N, Bhatnagar S, Bhutta ZA, Brooks A, Chadha M, Chisaka N, Chou M, Clara AW, Colbourn T, Cutland C, D'Acremont V, Echavarria M, Gentile A, Gessner B, Gregory CJ, Hazir T, Hibberd PL, Hirve S, Hooli S, Iqbal I, Jeena P, Kartasasmita CB, King C, Libster R, Lodha R, Lozano JM, Lucero M, Lufesi N, MacLeod WB, Madhi SA, Mathew JL, Maulen-Radovan I, McCollum ED, Mino G, Mwansambo C, Neuman MI, Nguyen NTV, Nunes MC, Nymadawa P, O'Grady KF, Pape JW, Paranhos-Baccala G, Patel A, Picot VS, Rakoto-Andrianarivelo M, Rasmussen Z, Rouzier V, Russomando G, Ruvinsky RO, Sadruddin S, Saha SK, Santosham M, Singhi S, Soofi S, Strand TA, Sylla M, Thamthitiwat S, Thea DM, Turner C, Vanhems P, Wadhwa N, Wang J, Zaman SM, Campbell H, Nair H, Qazi SA, Nisar YB; World Health Organization Pneumonia Research Partnership to Assess WHO Recommendation (PREPARE) study group. Assembling a global database of child pneumonia studies to inform WHO pneumonia management algorithm: methodology and applicationsJ Glob Health. 2022. PMID 36579417.

McGonagle EA, Caravite DJ, Grundmeier RW, Schmidt SK, May LS, Cohen DM, Cruz AT, Tu SP, Bajaj L, Dayan PS, Mistry RD. Evaluation of an antimicrobial stewardship decision support for pediatric infectionsAppl Clin Inform. 2023. PMID 36754066.

Florin TA, Melnikow J, Gosdin M, Ciuffetelli R, Benedetti J, Ballard D, Gausche-Hill M, Kronman MP, Martin LA, Mistry RD, Neuman MI, Palazzi DL, Patel SJ, Self WH, Shah SS, Shah SN, Sirota S, Cruz AT, Ruddy R, Gerber JS, Kuppermann N. Developing consensus on clinical outcomes for children with mild pneumonia: a Delphi studyJ Pediatr Infect Dis Soc. 2023. PMID 36625856.

Cruz AT, Starke JR. Clinical worsening in an adolescent with pleural tuberculosisJ Adolsc Health. 2023. PMID 36567181.

Chernick LS, Bugaighis M, Britton L, Cruz AT, Goyal MK, Mistry RD, Reed JL, Bakken S, Santelli JS, Dayan PS. Factors influencing the conduction of confidential conversations with adolescents in the emergency department: a multicenter, qualitative analysisAcad Emerg Med. 2022. 36478023.

Cruz AT, Tanverdi MS, Swartz SJ, Dayan PS, Combs VA, Lubell TR. Frequency of bacteremia and urinary tract infection in pediatric renal transplant recipientsPediatr Infect Dis J. 2022. PMID 36102710. 

Cameron LH, Cruz AT. Childhood tuberculosisCurr Opin Infect Dis. 2022. PMID 35947056.

Mahajan P, VanBuren JM, Tzimenatos L, Cruz AT, et al. Serious bacterial infections in young febrile infants with positive urinalysis resultsPediatrics. 2022. PMID 36097858.

Pruitt CM, Nigrovic LE, Freedman SB, Bradin SA, Curtis SJ, Lyons TW, Miller AS, Okada PJ, Schmidt SM, Schnadower D, Thomson JE, Cruz ATComprehensiveness of testing among herpes simplex virus infected infants: a multicenter cohort studyPediatr Infect Dis J. 2022. PMID 35797706.  

Click ES, Song R, Smith JP, Mchembere W, Fajans M, Hariri P, Okeyo E, McCarthy KD, Gethi D, Odeny L, Musau S, Okumu A, Orwa J, Perez-Velez CM, Wright CA, Andres M, Marais BJ, Schaaf HS, Graham SM, Cruz AT, Cain KP. Performance of Xpert MTB/RIF and mycobacterial culture on multiple specimen types for diagnosis of tuberculosis disease in young children and clinical characterization according to standardized research case definitionsPediatr Infect Dis J. 2022. PMID 35703284.  

Kaplan RL, Cruz AT, Freedman SB, Smith K, Freeman J, Lane RD, Michelson KA, Marble RD, Middelberg LK, Bergmann KR, McAneney C, Noorbakhsh, Pruitt C, Shah N, Badaki-Makun O, Schnadower D, Thompson AD, Blackstone MM, Abramo TJ, Srivastava G, Avva U, Samuels-Kalow M, Morientes O, Kannikeswaran N, Chaudhari PP, Strutt J, Vance C, Haines E, Khanna K, Gerard J, Bajaj L. Omphalitis and concurrent serious bacterial infectionPediatrics. 2022. PMID 35441224.

Cruz AT, Denison MR. Integrating SARS-CoV-2 antibody results in children into pandemic responsePediatrics. 2022. PMID 35301523.  

Swamy P, Duran C, Gupta A, Misra S, Fredricks K, Cruz ATDriving to reduce socioeconomic barriers to latent tuberculosis infection care: a mobile pediatric treatment programJ Public Health Manag Pract. 2022. PMID 35121709.

Rees CA, Colbourn T, Hooli S, et al. Derivation and validation of a novel risk assessment tool to identify children aged 2-59 months at risk of hospitalised pneumonia-related mortality in 20 countriesBMJ Glob Health. 2022. PMID 35428680.

O'Bryant SC, Momin Z, Camp E, Jones J, Meskill SLongitudinal evaluation of pediatric respiratory infections. J Clin Virol. 2022. PMID 35101733.

Baumann BM, Rodriguez RM, DeLaroche AM, Rayburn D, Eucker SA, Nadeau NL, Drago LA, Cullen D, Meskill SD, Bialeck S, Gillman M. Factors associated with parental acceptance of COVID-19 vaccination: a multicenter pediatric emergency department cross-sectional analysisAnn Emerg Med. 2022. PMID 35525709.

Depinet H, Macias CG, Balamuth F, Lane RD, Luria J, Melendez E, Myers SR, Patel B, Richardson T, Zaniletti I, Paul R; American Academy of Pediatrics Pediatric Septic Shock Collaborative (PSSC) Investigators. Pediatric septic shock collaborative improves emergency department sepsis care in childrenPediatrics. 2022. PMID 35229124.  

Gardiner MA, Allen CH, Singh NV, Tresselt E, Young A, Hurley KK, Wilkinson MH. Evaluation of a pediatric early warning score as a predictor of occult invasive bacterial infection in the pediatric emergency departmentPediatr Emerg Care. 2022. PMID 34711757. 

Souganidis ES, Patel B, Sampayo EM. Physician-specific utilization of an electronic best practice alert for pediatric sepsis in the emergency departmentPediatr Emerg Care. 2022. PMID 35696307.    

Greenfield BW, Lowery BM, Starke HE, Mayorquin L, Stanford C, Camp EA, Cruz ATFrequency of serious bacterial infections in young infants with and without viral respiratory infections. Am J Emerg Med. 2021. PMID 34879497.

Cruz AT, Nigrovic LE, Xie J, Mahajan P, Thomson JE, Okada PJ, Uspal NG, Mistry RD, Garro A, Schnadower D, Kulik DM, Curtis SJ, Miller AS, Fleming AH, Lyons TW, Balamuth F, Arms JL, Louie J, Aronson PL, Thompson AD, Ishimine PT, Schmidt SM, Pruitt CM, Shah SS, Grether-Jones KL, Bradin SA, Freedman SB. Predictors of invasive herpes simplex virus in young infantsPediatrics. 2021. PMID 34446535.

Kaplan RL, Cruz AT, Michelson KA, McAneney C, Blackstone MM, Pruitt CM, Shah N, Noorbakhsh KA, Abramo TJ, Marble RD, Middelberg L, Smith K, Kannikeswaran N, Schnadower D, Srivastava G, Thompson AD, Lane RD, Freeman JF, Bergmann KR, Morientes O, Gerard J, Badaki-Makun O, Avva U, Chaudhari PP, Freedman SB, Samuels-Kalow M, Haines E, Strutt J, Khanna K, Vance C, Bajaj L. Neonatal mastitis and concurrent serious bacterial infectionPediatrics. 2021. PMID 34187909.

Rees CA, Hooli S, King C, McCollum ED, Colbourn T, Lufesi N, Mwansambo C, Lazzerini M, Madhi SA, Cutland C, Nunes M, Gessner BD, Basnet S, Kartasasmita CB, Mathew JL, Zaman SMAU, Paranhos-Baccala G, Bhatnagar S, Wadhwa N, Lodha R, Aneja S, Santosham M, Picot VS, Sylla M, Awasthi S, Bavdekar A, Pape JW, Rouzier V, Chou M, Rakoto-Andrianarivelo M, Wang J, Nymadawa P, Vanhems P, Russomando G, Asghar R, Banajeh S, Iqbal I, MacLeod W, Maulen-Radovan I, Mino G, Saha S, Singhi S, Thea DM, Clara AW, Campbell H, Nair H, Falconer J, Williams LJ, Horne M, Strand T, Qazi SA, Nisar YB, Neuman MI; World Health Organization PREPARE study group48. External validation of the RISC, RISC-Malawi, and PERCH clinical prediction rules to identify risk of death in children hospitalized with pneumoniaJ Glob Health. 2021. 34737862.

Cruz AT, Zeichner SL. Duration of effective antibody levels after COVID-19Pediatrics. 2021. PMID 34158313.

Ikeda S, Cruz AT, Starke JR. Epidemiology and clinical characteristics of childhood TB identified using active and passive case findingInt J Tuberc Lung Dis. 2021. PMID 34049610.

Starke JR, Cruz ATDiagnosing childhood tuberculosis: a small step forwardJAMA Pediatr. 2021. PMID 33616639.

Lin CY, Xie J, Freedman SB, McKee RS, Schnadower D, Tarr PI, Finkelstein Y, Desai NM, Lane RD, Bergmann KR, Kaplan RL, Hariharan S, Cruz AT, et al. Predicting adverse outcomes for shiga toxin-producing Escherichia coli infections in emergency departmentsJ Pediatr. 2021. PMID 33417918.

McLaren SH, Cruz AT, Yen K, et al. Invasive bacterial infections in afebrile infants diagnosed with acute otitis mediaPediatrics. 2021. PMID 33288730.

Singh NV, Gabriele GA, Wilkinson MH. Sucralfate as an adjunct to analgesia to improve oral intake in children with infectious oral ulcers: a randomized, double-blind, placebo-controlled trialAnn Emerg Med. 2021. PMID 33867179.

McCollum ED, King C, Ahmed S, Hanif AAM, Roy AD, Islam AA, Colbourn T, Schuh HB, Ginsburg AS, Hooli S, Chowdhury NH, Rizvi SJR, Begum N, Baqui AH, Checkley W. Defining hypoxaemia from pulse oximeter measurements of oxygen saturation in well children at low altitude in Bangladesh: an observational study. BMJ Open Respir Res. 2021. PMID 34728475.

Neubauer HC, Hall M, Lopez MA, Cruz AT, et al. Antibiotic regimens and associated outcomes in children hospitalized with staphylococcal scalded skin syndrome. J Hosp Med. 2021. PMID 33617441.

Vo AT, Liu DR, Schmidt AR, Festekijan A. Capillary blood gas in infants with bronchiolitis: can end-tidal capnography replace it? Am J Emerg Med. 2021. PMID: 33915447.

Starosolski Z, Admane P, Dunn J, Kaziny B, Huisman TAGM, Annapragada A. Design of 3D-printed nasopharyngeal swabs for children is enabled by radiographic imagingAJNR Am J Neuroradiol. 2020. PMID: 32855191.

Colbourn T, King C, Beard J, Phiri T, Mdala M, Zadutsa B, Makwenda C, Costello A, Lufesi N, Mwansambo C, Nambiar B, Hooli S, French N, Bar Zeev N, Qazi SA, Bin Nisar Y, McCollum ED. Predictive value of pulse oximetry for mortality in infants and children presenting to primary care with clinical pneumonia in rural Malawi: a data linkage studyPLoS Med. 2020. PMID 33095763.

Cruz AT, Lane RD, Balamuth F, Aronson PL, Ashby DW, Neuman MI, Souganidis ES, Alpern ER, Schlapbach LJ. Updates on pediatric sepsis. J Am Coll Emerg Physicians Open. 2020. PMID: 33145549. 

Cruz AT, Shaman J, Dayan PS. The Challenge of Clearly Counting COVID-19 Cases in Children.  Pediatrics. 2020. PMID: 32994181.

Zeichner SL, Cruz AT. Multisystem Inflammatory Syndrome in Children and SARS-CoV-2 Serology. Pediatrics. 2020.PMID: 32973121. 

Chiang SS, Dolynska M, Rybak NR, Cruz AT, Aibana O, Sheremeta Y, Petrenko V, Mamotenko A, Terleieva I, Horsburgh CR Jr, Jenkins HE. Clinical manifestations and epidemiology of adolescent tuberculosis in Ukraine. ERJ Open Res. 2020. PMID: 32964003. 

Alpern ER, Kuppermann N,  Blumberg S, Roosevelt G, Cruz AT, Nigrovic LE, Browne LR, VanBuren JM, Ramilo O, Mahajan P; PEDIATRIC EMERGENCY CARE APPLIED RESEARCH NETWORK (PECARN). Time to Positive Blood and Cerebrospinal Fluid Cultures in Febrile Infants ≤60 Days of Age.  Hosp Pediatr. 2020. PMID: 32868377.

Lamb GS, Cruz AT, Camp EA, Javier M, Montour J, Piper T, Shah UA, Starke JR. Tuberculosis in Internationally Displaced Children Resettling in Harris County, Texas, USA, 2010-2015. Emerg Infect Dis. 2020. PMID: 32687465. 

Cruz AT, Ellison AM, Johnson TJ. Perspectives on Urinary Tract Infection and Race. JAMA Pediatr. 2020. PMID: 32663241 

Tsze DS, Cruz AT, Mistry RD, Gonzalez AE, Ochs JB, Richer L, Kuppermann N, Dayan PS. Interobserver Agreement in the Assessment of Clinical Findings in Children with Headaches.  J Pediatr. 2020. PMID: 32446483.

Cruz AT, Schwartzman K, Kitai I. Fighting a hidden epidemic: expanding tuberculosis preventive treatment to the youngest household contacts.  Int J Tuberc Lung Dis. 2020. PMID: 32317055. 

Lyons TW, Garro AC, Cruz AT, Freedman SB, Okada PJ, Mahajan P, Balamuth F, Thompson AD, Kulik DM, Uspal NG, Arms JL, Nigrovic LE; HERPES SIMPLEX VIRUS STUDY GROUP OF THE PEDIATRIC EMERGENCY MEDICINE COLLABORATIVE RESEARCH COMMITTEE (PEM CRC). Performance of the Modified Boston and Philadelphia Criteria for Invasive Bacterial Infections.  Pediatrics. 2020. PMID: 32205466.

Green RS, Cruz AT, Freedman SB, Fleming AH, Balamuth F, Pruitt CM, Lyons TW, Okada PJ, Thompson AD, Mistry RD, Aronson PL, Nigrovic LE; Herpes Simplex Virus Study Group of the Pediatric Emergency Medicine Collaborative Research Committee (PEM CRC). The Champagne Tap: Time to Pop the Cork? Acad Emerg Med. 2020. PMID: 32187765.

Cruz AT, Zeichner SL. COVID-19 in Children: Initial Characterization of the Pediatric Disease. Pediatrics. 2020. PMID: 32179659. 

Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.  Pediatr Crit Care Med. 2020. PMID: 32032273.

Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.  Pediatr Crit Care Med. 2020. PMID: 32032264.

Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children.  Intensive Care Med. 2020. PMID: 32030529.

Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children.  Intensive Care Med. 2020. PMID: 32030528. 

Snow KJ, Cruz AT, Seddon JA, Ferrand RA, Chiang SS, Hughes JA, Kampmann B, Graham SM, Dodd PJ, Houben RM, Denholm JT, Sawyer SM, Kranzer K. Adolescent tuberculosis.  Lancet Child Adolesc Health. 2020. PMID: 31753806. 

McKee RS, Schnadower D, Tarr PI, Xie J, Finkelstein Y, Desai N, Lane RD, Bergmann KR, Kaplan RL, Hariharan S, Cruz AT, Cohen DM, Dixon A, Ramgopal S, Rominger A, Powell EC, Kilgar J, Michelson KA, Beer D, Bitzan M, Pruitt CM, Yen K, Meckler GD, Plint AC, Bradin S, Abramo TJ, Gouin S, Kam AJ, Schuh A, Balamuth F, Hunley TE, Kanegaye JT, Jones NE, Avva U, Porter R, Fein DM, Louie JP, Freedman SB; Pediatric Emergency Medicine Collaborative Research Committee and Pediatric Emergency Research Canada. Predicting Hemolytic Uremic Syndrome and Renal Replacement Therapy in Shiga Toxin-producing Escherichia coli-infected Children.  Clin Infect Dis. 2020. PMID: 31125419.

Chiang SS, Park S, White EI, Friedman JF, Cruz AT, Del Castillo H, Lecca L, Becerra MC, Seddon JA. Using Changes in Weight-for-Age z Score to Predict Effectiveness of Childhood Tuberculosis Therapy. J Pediatric Infect Dis Soc. 2020. PMID: 30715497. 

Nolan MS, Cruz AT, Erickson T. Retrospective Chart Analysis of Child and Adolescent Trichomonas vaginalis Infection in Houston, Texas.  J Pediatric Infect Dis Soc. 2020. PMID: 30624683.

Souganidis E, Abbadessa MK, Ku B, Minich C, Lavelle J, Zorc J, Balamuth F. Analysis of Missed Sepsis Patients in a Pediatric Emergency Department With a Vital Sign-Based Electronic Sepsis Alert.  Pediatr Emerg Care. 2020. PMID: 33003131.

Thomas VA, Crouse HL, Murray KO, Hsu DC, Camp EA, Cruz AT. Emergency medicine providers' knowledge and management of pediatric tropical diseases: a needs assessmentPediatr Emerg Care. 2020. PMID 29538263.