Kochel Lab Research Projects

Much of what we know about autism, we know because families have participated in research studies. At Baylor College of Medicine and Texas Children’s Hospital, research is an important part of clinical care and an essential part of our overall mission. Many studies offer a direct benefit to participants and their families, including additional information that may inform their medical care, treatments, or educational programming and connections with other affected families. Participating in autism research is also an opportunity for families to get their voices heard and advocate for themselves and future families. Ask your doctor about research opportunities during your next visit! Learn what families say about their experiences working with us.

• Research Participation Awareness List (PALs Program)
• PALs Program Registration: English / Español
• SPARK for Autism

• Causes and Consequences of Developmental Regression in ASD
• Parents’ Perceptions about ASD
• Vaccine Hesitancy

Research Background

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social-communication skills, as well as the presence of restricted, repetitive patterns of behaviors or interests. Symptoms usually present during the first two years of life, and although children can be reliably diagnosed as young as 18 months, the average age of diagnosis in the United States currently is four years. Most scientists believe that ASD is caused by a combination of genetic and environmental factors. While advances in technology allow for continuous improvements in genetic-testing capabilities, a genetic explanation is currently identified in about 25 percent of affected individuals. Researchers today continue to investigate etiological factors, biological markers for early detection, and the most effective treatment approaches. The participation of families is critical to our being able to answer important questions about ASD and facilitate the best outcomes for all affected individuals.

• Simons Simplex Collection (SSC)
• Simons Variation in Individuals Project (SVIP)
• SynapDx Autism Spectrum Disorder Gene Expression Analysis Study (STORY)