Email

sgh@bcm.edu

Positions

Professor

Smith Breast Center - Hilsenbeck
Baylor College of Medicine
Houston, TX US

Director, Quantitative Sciences Share Resource

Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States

Faculty Senator

Baylor College of Medicine
Houston, Texas United States

Addresses

BCM-Cullen Building (Office)

Room: BCMC-333A
Houston, TX 77030
United States

Education

Ph.D. from University Of Miami

01/1990 - Miami, FL United States

Certifications

Fellow

American Statistical Association

PStat

American Statistical Association

Certified Professional Statistician

Professional Interests

• Design and statistical analysis of translational experiments and clinical trials

Professional Statement

Dr. Hilsenbeck has a PhD in applied biostatistics, and has long-standing interests in biostatistical and informatics collaboration, especially in cancer research. She is the statistician of record on a number of investigator-initiated multi-center clinical trials and leads several of the biostatistics and informatics focused resources at Baylor, including: Biostatistics and Informatics Shared Resource, Duncan Cancer Center; and Biostatistics, Duncan Institute for Translational Research.
Dr. Hilsenbeck's personal research interests focus on design and analysis of prognostic and predictive biomarker studies. She is also committed to teaching. She serves on mentoring committees, leads the biostatistics course for TBMM graduate students (elective to satisfy biostatistics training requirement for other programs), and is regularly invited to teach in national and international workshops.

Websites

Selected Publications

• Yuan Y, Hess KR, Hilsenbeck SG, Gilbert MR "Bayesian Optimal Interval Design: A Simple and Well-Performing Design for Phase I Oncology Trials.." 2016;22:4291-4301. Pubmed PMID: 27407096
• Kessler JD, Kahle KT, Sun T, Meerbrey KL, Schlabach MR, Schmitt EM, Skinner SO, Xu Q, Li MZ, Hartman ZC, Rao M, Yu P, Dominguez-Vidana R, Liang AC, Solimini NL, Bernardi RJ, Yu B, Hsu T, Golding I, Luo J, Osborne CK, Creighton CJ, Hilsenbeck SG, Schiff R, "A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis.." Science. 2012 Jan 20;335(6066):348-53. Pubmed PMID: 22157079
• Karlin KL,Mondal G,Hartman JK,Tyagi S,Kurley SJ,Bland CS,Hsu TY,Renwick A,Fang JE,Migliaccio I, Callaway C,Nair A,Dominguez-Vidana R,Nguyen DX,Osborne CK,Schiff R,Yu-Lee LY,Jung SY,Edwards DP, Hilsenbeck SG,Rosen JM,Zhang XH,Shaw CA,Couch FJ,Westbrook TF "The Oncogenic STP Axis Promotes Triple-Negative Breast Cancer via Degradation of the REST Tumor Suppressor.." 2014;9(4):1318-32.
• Hertz DL, Kidwell KM, Hilsenbeck SG, Oesterreich S, Osborne CK, Philips S, Chenault C, Hartmaier RJ, Skaar TC, Sikora MJ, Rae JM. "CYP2D6 genotype is not associated with survival in breast cancer patients treated with tamoxifen: results from a population-based study.." Breast Cancer Res Treat.. 2017; Pubmed PMID: 28730340

Memberships

American Statistical Association

Member

Baylor College of Medicine Faculty Senate

Senator, Duncan Cancer Center (11/2015)