Baylor College of Medicine

Daniel A Gorelick, Ph.D.

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Gorelick

Daniel A Gorelick, Ph.D.

Associate Professor

Email

gorelick@bcm.edu

Positions

Associate Professor: Center for Precision Environmental Health
Department of Molecular & Cellular Biology
Baylor College of Medicine
Houston, TX US

Addresses

Alkek Tower (Office)
: Room: ALKT-N1317.07
Houston, TX 77030
United States
gorelick@bcm.edu

Education

BA from University of Pennsylvania: Philadelphia, PA

PhD from Johns Hopkins University School of Medicine: Baltimore, MD; Cellular & Molecular Medicine

Postdoctoral Fellowship at US Department of State: 08/2009 - Washington, DC; AAAS Science & Technology Policy Fellowship

Postdoctoral Fellowship at Carnegie Institution for Science: 08/2012 - Baltimore, MD; Developmental Biology, Endocrinology

Professional Interests

Cell signaling
Environmental influence on organ formation & function
Zebrafish genetics

Professional Statement

Using genetic tools in zebrafish, we study how endogenous and environmental hormones influence the development and function of the heart, brain, gonad and other tissues.

Selected Publications

RM Cabrera, JP Souder, JW Steele, L Yeo, G Tukeman, DA Gorelick, RH Finnell "The Antagonism of Folate Receptor by Dolutegravir: Developmental Toxicity Reduction by Supplemental Folic Acid." AIDS. 2019; Pubmed PMID: 31259764
JP Souder, DA Gorelick "ahr2, But Not ahr1a or ahr1b, Is Required for Craniofacial and Fin Development and TCDD-dependent Cardiotoxicity in Zebrafish." Toxicological Sciences. 2019; Pubmed PMID: 30907958
HE Edwards, MJ Elizalde, JP Souder, DA Gorelick "Hemato-vascular specification requires arnt1 and arnt2 genes in zebrafish embryos." Development. 2023; Pubmed PMID: 37039097
HE Edwards, DA Gorelick "The evolution and structure/function of bHLH-PAS transcription factor family." Biochem Society Transactions. 2022; Pubmed PMID: 35695677

LS Treviño, DA Gorelick "The Interface of Nuclear and Membrane Steroid Signaling." Endocrinology. 2021; Pubmed PMID: 34038515
V Zadmajid, DA Gorelick "Testosterone acts through membrane protein GPRC6A to cause cardiac edema in zebrafish embryos." bioRxiv. 2023;
CM Crowder, CS Lassiter, DA Gorelick "Nuclear Androgen Receptor Regulates Testes Organization and Oocyte Maturation in Zebrafish." Endocrinology. 2018; Pubmed PMID: 29272351
SN Romano, HE Edwards, JP Souder, KJ Ryan, X Cui, DA Gorelick "G protein-coupled estrogen receptor regulates embryonic heart rate in zebrafish." PLOS Genetics. 2017; Pubmed PMID: 29065151

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Memberships

Society of Toxicology

Society for Developmental Biology

Funding

Investigating aryl hydrocarbon receptor-cofactor interactions that mediate toxicity

Plausible Causative Mechanism for Dolutegravir Developmental Toxicity