Positions
- Associate Professor
-
Center for Gene Therapy
Baylor College of Medicine
Houston, TX US
- Member
-
Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States
Addresses
- TX Childs Feigin Ctr (Lab)
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Room: TXFC-1770
Houston, TX 77030
United States
- TX Childs Feigin Ctr (Office)
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Room: TXFC-1770
Houston, TX 77030
United States
Professional Interests
- The application of helper-dependent adenoviral vectors (HDAds) to cancer immunotherapy
- Combinatorial cancer immunotherapy with gene therapy and cell therapy
- Evaluation of cancer immunotherapy in humanized mouse model
- Evaluation tumor immune microenvironment in pre-clinical and clinical samples
- In vivo CAR-T cell generation using adenoviral vector
Websites
Selected Publications
- Rosewell Shaw A, Porter CE, Watanabe N, Tanoue K, Sikora A, Gottschalk S, Brenner MK, Suzuki M "Adenovirotherapy Delivering Cytokine and Checkpoint Inhibitor Augments CAR T Cells against Metastatic Head and Neck Cancer." Molecular Therapy. 2017; Pubmed PMID: 28974431
- Tanoue K, Rosewell Shaw A, Watanabe N, Porter C, Rana B, Gottschalk S, Brenner M, Suzuki M "Armed Oncolytic Adenovirus-Expressing PD-L1 Mini-Body Enhances Antitumor Effects of Chimeric Antigen Receptor T Cells in Solid Tumors." Cancer Research. 2017; Pubmed PMID: 28235763
- Rosewell Shaw A, Suzuki M "Oncolytic Viruses Partner With T-Cell Therapy for Solid Tumor Treatment." ; Pubmed PMID: 30298067
- "Oncolytic adeno-immunotherapy modulates the immune system enabling CAR T-cells to cure pancreatic tumors." 2021; Pubmed PMID: 33742099
- "Oncolytic Adenovirus Armed with BiTE, Cytokine, and Checkpoint Inhibitor Enables CAR T Cells to Control the Growth of Heterogeneous Tumors." 2020; Pubmed PMID: 32145203
- "Ultralow-dose binary oncolytic/helper-dependent adenovirus promotes antitumor activity in preclinical and clinical studies." 2023; Pubmed PMID: 36989357
Projects
- Combination immunotherapy with oncolytic adeno-immunotherapy and CAR cell therapy for solid tumor treatment
- In vivo CAR-T cell generation using adenoviral vector
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