TRISH Research
Deep space exploration – beyond low Earth orbit, to the Moon, Mars, and beyond – presents unique mental, physical, and emotional challenges. To thrive in deep space, humans will need practical solutions to problems like neurocognitive changes, radiation exposure and other stressors. TRISH leads a national effort in translating emerging terrestrial biomedical research and technology development into applied human risk-mitigation strategies, helping humans thrive wherever they explore, in space or on Earth.
TRISH funds both early-stage, high-risk research with the potential for high impact as well as more mature, translation-ready technologies that can be employed in spaceflight. This forward-looking work could create a paradigm shift in healthcare during space exploration enabling us to reach new frontiers in healthcare on Earth.
TRISH Scientific Initiatives Overview
EXPAND: Advancing Commercial Space Research
As commercial spaceflight takes off, the EXPAND Program seizes new opportunities to study human adaption and physiology. TRISH works with commercial spaceflight providers and their participants to increase engagement in human research and collect essential biomedical data before, during and after spaceflight. This information is securely maintained in the Institute’s centralized EXPAND database, the world’s first and only private space health research repository. It will offer researchers unparalleled access to biological samples and data from a diverse pool of spaceflight participants.
HERMES: A Medical System Architecture
To enable an effective health and performance system, healthcare providers and spaceflight crews need access to current and comprehensive health and performance data to make evidence-based decisions. However, there will be a variety of sources before, during and after a mission that contribute health and performance data creating a fragmented record and inconsistent access. TRISH’s goal is to enable a robust and democratized heath record that accompanies the astronaut making health information and data from a variety of sources useful and accessible, even when the crew is far from Earth.
SENTINEL: Tissue-Chips
TRISH is accelerating human tissue chips system technologies to provide an advanced biological platform to study long-duration deep space exposure. These advanced systems will be automated and have embedded analytic capability allowing researchers to characterize the biological effects of deep space exposure and test personalized countermeasures to protect humans exploring space without requiring samples be returned to Earth for analysis.
Learn more about TRISH scientific initiatives in our Broad Institute Announcement (BIA):
